DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PHGPx and gpx-1

DIOPT Version :9

Sequence 1:	NP_728869.1	Gene:	PHGPx / 38413	FlyBaseID:	FBgn0035438	Length:	238	Species:	Drosophila melanogaster
Sequence 2:	NP_492598.1	Gene:	gpx-1 / 184981	WormBaseID:	WBGene00009165	Length:	163	Species:	Caenorhabditis elegans

Alignment Length:	161	Identity:	80/161 - (49%)
Similarity:	111/161 - (68%)	Gaps:	5/161 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 ASIYEFTVKDTHGNDVSLEKYKGKVVLVVNIASKCGLTKNNYEKLTDLKEKYGERGLVILNFPCN 144
            :|:|:|.||:.:|:||||..|||||:::||:||:||||..||.:|.:|.:.|.:.||.:|.||||
Worm     2 SSVYDFNVKNANGDDVSLSDYKGKVLIIVNVASQCGLTNKNYTQLKELLDVYKKDGLEVLAFPCN 66

  Fly   145 QFGSQMP--EADGEAMVCHLRDSKADIGEVFAKVDVNGDNAAPLYKYLKAKQTGTLGSGIKWNFT 207
            ||..|.|  |.|.:|.|.   |.......:|.|:|||||..:||:|:||.::.|.:...||||||
Worm    67 QFAGQEPSCEIDIQAFVA---DKFKFEPTLFQKIDVNGDKQSPLFKFLKNEKGGFMFDAIKWNFT 128

  Fly   208 KFLVNKEGVPINRYAPTTDPMDIAKDIEKLL 238
            ||||.::|..|.|:.|||||.|:.|||::.|
Worm   129 KFLVGRDGKIIKRFGPTTDPKDMEKDIKEAL 159

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PHGPx	NP_728869.1	GSH_Peroxidase	81..234	CDD:238207	77/154 (50%)
gpx-1	NP_492598.1	GSH_Peroxidase	3..155	CDD:238207	77/154 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	110	1.000	Domainoid score	I3951
eggNOG	1	0.900	-	-		E1_COG0386
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H133958
Inparanoid	1	1.050	161	1.000	Inparanoid score	I2852
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48732
OrthoDB	1	1.010	-	-		D1483113at2759
OrthoFinder	1	1.000	-	-		FOG0000791
OrthoInspector	1	1.000	-	-		mtm4796
orthoMCL	1	0.900	-	-		OOG6_100297
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16331
SonicParanoid	1	1.000	-	-		X276
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.810