Protein Alignment Strip and csc2

DIOPT Version :10

• Sequence 1: NP_647806.2
• Gene: Strip / 38412
• FlyBaseID: FBgn0035437
• Length: 927
• Species: Drosophila melanogaster
• Sequence 2: NP_595536.1
• Gene: csc2 / 2540495
• PomBaseID: SPBC27B12.04C
• Length: 817
• Species: Schizosaccharomyces pombe
• Alignment Length: 868
• Identity: 184/868 - (21%)
• Similarity: 319/868 - (36%)
• Gaps: 199/868 - (22%)

  Fly    61 DADANCDGPDLDFVYADVDGYQNEIAELYSYTEFSEFQMNVKAFEDQMELY------DLPPNWQK 119
            |:.|:...| ::|.....|..::::...:...|......| |.|..::.:|      .|..||..
pombe    22 DSPASKHKP-MEFKGTSKDDLEDDLNSFFDCEEELFLSAN-KIFYSKLRVYQTVRHWSLKQNWSS 84

  Fly   120 QDSASQRGIVMKLVDQLEVSDRSFRMQAARCILYLAQGCWAEVQSDEEQHQITRDNVLVLYQLG- 183
            .....:|..::....:|. |....|..|...|||:|.|.:..|.|.||......:||.:|.:..
pombe    85 MSLDQKRNFILHCHHELS-SGELLRNSALYSILYIAAGAYDSVGSFEEHVHSISENVYLLREFDI 148

  Fly   184 ---VFASFIDLLNMEIESACSPDIVAVKITNVTLVDSTD---IRVILSVLYIITETIRDEKEKGS 242
               |::.||:.......|              .|.:|.|   :.::||:::........:|
pombe   149 PKTVYSLFIEWNRTRKHS--------------FLDNSRDEGFLNLLLSLMFFFLTLNNTDK---- 195

  Fly   243 EDYRELADSFVQEINSPLPDGELLAVKLLGMIT---RFCSGAAPQFPMKKVVLLLWKVSLLGLGG 304
                    :::..|.|..|......|||...||   :..........:||:..|::||.:...|.
pombe   196 --------TWIHSIRSLNPPVLPTLVKLFIDITSDYQLNLDKVIHSSLKKLSFLIFKVCIRLWGS 252

  Fly   305 MDVLKNLKNEYRLKVGLEPITEDTLEVTKCMRASSPPATATDILENQYPKRNFKRSLMKQRFLDE 369
            ...|:      ..|.||..:...:....|      |..||.|     |.....:.:.....|.|.
pombe   253 QSYLQ------EKKAGLAEVLNISTSQQK------PKTTALD-----YEVFRHEMATKFSSFADS 300

  Fly   370 --PEQIDMEMGGNEGQNNANNGSGNGGNGEEELSQYYRPYDDPSSSASTTSTANPNNQPSLTQPP 432
              |..:|.|........|.::              :::     ||..|:|...:|.| |||....
pombe   301 YYPVPLDREQAHILPTLNTDS--------------FHK-----SSFISSTRLCSPEN-PSLLVNT 345

  Fly   433 AAVPPVQITARLPWTPKVRQKDIDQFLDISRNKFIGYSLIGDHESLAGLPQPIHEGFKTLQRHMY 497
            |...  :::||.           :||   ..|:.:.:....:.|.|. :|..:.|.....|....
pombe   346 AKTS--KMSARR-----------EQF---QTNQNLPFCFTPNLEKLT-IPYSVTEAANVFQNKTK 393

  Fly   498 MSLADVQIKKEEDIAR--------------------NPISTHEDE---IKLTPAEVLYQAILP-- 537
            .:||..|:..|.::.|                    .|..:.|.|   :|.....  |..:.|
pombe   394 RTLAVEQLLSERELLRRFTLQQRLVADLHEFYNSVKGPAHSFETEDPVLKFVSQS--YDDLFPYM 456

  Fly   538 -NLPQYMIALL-----KV---LLAASPTSKSKTESI--NIMADVLPRKMPLTATQSTKLTVDIG- 590
             |..|..:.|.     ||   .:.|..:|.:..:.|  |.:.|....::...|.::.|..|.|.
pombe   457 DNFIQLAVQLFYHISKKVNCLYVEAFSSSDAVLQRIQDNAVVDSPTEELSEQAARNRKSNVKIEY 521

  Fly   591 ------------------RHKEIIVKAVSAIILLYLKHFKINHVYQFEFMSQHLVFANCIPLVLK 637
                              .:.|.::.::|::.|:.||.|:::||.:||.:: .|::.|..   |:
pombe   522 TEDFATGFAISGEISHSINNLEFVLYSLSSLFLMMLKWFRLSHVLRFERLA-FLLYENHF---LE 582

  Fly   638 FFNQTITE---YVNTKNSIPLLDFPSCVIGEQPDLSGDSFVYGGEM----------SDKSYSWRN 689
            .||:.:||   ..||:..:      .||       .|..|.|..:|          ..::.|.||
pombe   583 IFNRHLTEGDCNRNTEKDV------KCV-------RGGFFSYSSKMYKYDRVSIPVITRASSSRN 634

  Fly   690 VFSCINLLRILNKLIKWKHSRVMMLVVFKSAPILKKTLKVRHAMMQLYVLKLLKMQTKYLGRQWR 754
            :...:|.||:|.|:.|:.:.|..::........|||.|.:.|..::||.||:||:...:||.:|:
pombe   635 LLITMNCLRVLEKVCKYSNIRKEIIARSNLHENLKKLLAIPHDKLRLYALKVLKLSVPFLGLKWK 699

  Fly   755 KSNMKTMSAIYAKVRHRLNDDWAFGNDLESRPWDFQAEECTLRACVDRFNLRRYPEATQKCGN-- 817
            ::||..::.||......|.|.|.|..:........|.:|..|...:..:::|.|   .:||.:
pombe   700 QANMSIITQIYLNCSLDLRDSWMFHENGSDTYRSAQLQETFLAILIRFYHIRLY---GKKCKSLY 761

  Fly   818 ------NGTAAQNAENAQQSNMM 834
                  .....::.|....||||
pombe   762 QFCILEEMRLKKSIEELAASNMM 784

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Strip	NP_647806.2	N1221	69..347	CDD:429737	60/293 (20%)
		DUF3402	482..810	CDD:463384	90/395 (23%)
csc2	NP_595536.1	N1221	30..308	CDD:429737	65/323 (20%)
		DUF3402	378..767	CDD:463384	92/410 (22%)