DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12016 and ATCAY

DIOPT Version :9

Sequence 1:	NP_647805.1	Gene:	CG12016 / 38411	FlyBaseID:	FBgn0035436	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_149053.1	Gene:	ATCAY / 85300	HGNCID:	779	Length:	371	Species:	Homo sapiens

Alignment Length:	116	Identity:	21/116 - (18%)
Similarity:	37/116 - (31%)	Gaps:	44/116 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 SLHDYFKGLRGAPLWNSPYTIGEVRLISQDDYFL----------------------PVEDKRHQR 65
            ||.||...:....|    |.|..:.|:..:||.:                      .:.|:|.::
Human   203 SLPDYHYIMENLFL----YVISSLELLVAEDYMIVYLNGATPRRRMPGIGWLKKCYQMIDRRLRK 263

  Fly    66 N----------------EALNA--INFELITSLDMAKMLNDIAHIIKGRHV 98
            |                .|::.  |:.:.|..:.....|.|:..:|...||
Human   264 NLKSLIIVHPSWFIRTVLAISRPFISVKFINKIQYVHSLEDLEQLIPMEHV 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12016	NP_647805.1	NRK1	6..255	CDD:238982	21/116 (18%)
ATCAY	NP_149053.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..54
		BNIP2	59..187	CDD:315215
		Required for interaction with KLC1. /evidence=ECO:0000250	115..120
		CRAL_TRIO_2	189..314	CDD:316255	19/114 (17%)
		Mediates interaction with GLS. /evidence=ECO:0000269\|PubMed:16899818	190..371		21/116 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	331..371
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0572
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900