DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12016 and UK/UPRT1

DIOPT Version :9

Sequence 1:	NP_647805.1	Gene:	CG12016 / 38411	FlyBaseID:	FBgn0035436	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_198903.1	Gene:	UK/UPRT1 / 834088	AraportID:	AT5G40870	Length:	486	Species:	Arabidopsis thaliana

Alignment Length:	227	Identity:	42/227 - (18%)
Similarity:	74/227 - (32%)	Gaps:	88/227 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 QWLVIGISGVTCGGKTT----LAHSLHDYFKGLRGAPLWNSPYTIGEVRLISQDDYFLPVEDKRH 63
            |..:||:||.|..||||    :...|||:                 .|.|::||.::..:..:..
plant    61 QPFIIGVSGGTASGKTTVCDMIIQQLHDH-----------------RVVLVNQDSFYRGLTSEEL 108

  Fly    64 QRNEALNAINFELITSLDMAKMLNDIAHIIKGRHVAPEPQEHLVTYANFEHYAQQFQQQYQYNAN 128
            ||   :...||:...:.|..::|                           |.|:..:
plant   109 QR---VQEYNFDHPDAFDTEQLL---------------------------HCAETLK-------- 135

  Fly   129 YYKQANGGVYQYPPQQHPRHHPHHQQHHHQHHQIQQQQQHIMSINAQIAAQLRDKKVNFLLVEGF 193
                 :|..||.|......|              |::......:||.          :.:::||.
plant   136 -----SGQPYQVPIYDFKTH--------------QRRSDTFRQVNAS----------DVIILEGI 171

  Fly   194 MIFNQPELLALCNIKYHFHLPYEKCFERRSKR 225
            ::|:...:..|.|:|.......:....||.:|
plant   172 LVFHDSRVRNLMNMKIFVDTDADVRLARRIRR 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12016	NP_647805.1	NRK1	6..255	CDD:238982	41/224 (18%)
UK/UPRT1	NP_198903.1	UMPK	64..262	CDD:238981	41/224 (18%)
UK/UPRT1	NP_198903.1	UPRTase	280..481	CDD:405383
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0572
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10285
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910