Protein Alignment CG12016 and NMRK1

DIOPT Version :10

• Sequence 1: NP_647805.1
• Gene: CG12016 / 38411
• FlyBaseID: FBgn0035436
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_001317607.1
• Gene: NMRK1 / 54981
• HGNCID: 26057
• Length: 203
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 65/279 - (23%)
• Similarity: 111/279 - (39%)
• Gaps: 94/279 - (33%)

  Fly     9 ISGVTCGGKTTLAHSLHDYFKGLRGAPLWNSPYTIGEVRLISQDDYFLPVEDKRHQRNEALNAIN 73
            ||.||..||||||.:|..:               :....:|||||:|.|..:....:|   ..:.
Human    12 ISCVTNSGKTTLAKNLQKH---------------LPNCSVISQDDFFKPESEIETDKN---GFLQ 58

  Fly    74 FELITSLDMAKMLNDIAHIIKGRHVAPEPQEHLVTYANFEHYAQQFQQQYQYNANYYKQANGGVY 138
            ::::.:|:|.||::.|:..:
Human    59 YDVLEALNMEKMMSAISCWM--------------------------------------------- 78

  Fly   139 QYPPQQHPRHHPHHQQHHHQHHQIQQQQQHIMSINAQIAAQLRDKKVNFLLVEGFMIFNQPELLA 203
                 :..||                   .::|.:.:.|     :::..|::|||::||...|..
Human    79 -----ESARH-------------------SVVSTDQESA-----EEIPILIIEGFLLFNYKPLDT 114

  Fly   204 LCNIKYHFHLPYEKCFERRSKRTYDPPDVTGYFELCVWPHYEKNFSEYRDCK-DITFLNGEIAKE 267
            :.|..|...:|||:|..|||.|.|.|||..|||:..|||.|.|...|.:|.. ::.:|:|..::|
Human   115 IWNRSYFLTIPYEECKRRRSTRVYQPPDSPGYFDGHVWPMYLKYRQEMQDITWEVVYLDGTKSEE 179

  Fly   268 KILAFVLHRIVHYF-KERC 285
            .:...|...::... |::|
Human   180 DLFLQVYEDLIQELAKQKC 198

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12016	NP_647805.1	NRK1	6..255	CDD:238982	59/245 (24%)
NMRK1	NP_001317607.1	NRK1	12..164	CDD:238982	58/243 (24%)