DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12016 and MBIP

DIOPT Version :9

Sequence 1:	NP_647805.1	Gene:	CG12016 / 38411	FlyBaseID:	FBgn0035436	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_057670.2	Gene:	MBIP / 51562	HGNCID:	20427	Length:	344	Species:	Homo sapiens

Alignment Length:	172	Identity:	24/172 - (13%)
Similarity:	52/172 - (30%)	Gaps:	72/172 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 NSPYTIGEVRLISQDDYFLPVEDKRHQRNEALNAINFELITSLDMAKMLNDIAHIIKGR-HVAPE 101
            |..::||:::           |:::|:.                     :|:..:.|.: |..||
Human   116 NDKFSIGDLQ-----------EEEKHKE---------------------SDLRDVKKTQIHFDPE 148

  Fly   102 PQEHLVTYANFEHYAQQF--QQQYQYNANYYKQ-------------------------------A 133
            ..:.....|..:.....|  ::|.:.|.|..::                               .
Human   149 VVQIKAGKAEIDRRISAFIERKQAEINENNVREFCNVIDCNQENSCARTDAIFTPYPGFKSHVKV 213

  Fly   134 NGGVYQYPPQQHPR------HHPHHQQHHHQHHQIQQQQQHI 169
            :..|..|.||..|.      |.|:.......:..::::.|:|
Human   214 SRVVNTYGPQTRPEGIPGSGHKPNSMLRDCGNQAVEERLQNI 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12016	NP_647805.1	NRK1	6..255	CDD:238982	24/172 (14%)
MBIP	NP_057670.2	Interaction with MAP3K12	172..344		11/84 (13%)
		Leucine-zipper 1. /evidence=ECO:0000255	271..285
		Leucine-zipper 2. /evidence=ECO:0000255	314..329
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157779
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930