DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12016 and Nmrk1

DIOPT Version :9

Sequence 1:	NP_647805.1	Gene:	CG12016 / 38411	FlyBaseID:	FBgn0035436	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	XP_008758512.1	Gene:	Nmrk1 / 499330	RGDID:	1564687	Length:	213	Species:	Rattus norvegicus

Alignment Length:	300	Identity:	73/300 - (24%)
Similarity:	111/300 - (37%)	Gaps:	113/300 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VIGISGVTCGGKTTLAHSLHDYFKGLRGAPLWNSPYTIGEVRLISQDDYFLPVEDKRHQRNEALN 70
            ||||.|||.|||||||.:|..               .:....:|||||:|.|..:.....|   .
  Rat     5 VIGIGGVTNGGKTTLAKNLQK---------------RLPNCSVISQDDFFKPESEIDIDEN---G 51

  Fly    71 AINFELITSLDMAKMLNDIAHIIK--GRHVAPEPQEHLVTYANFEHYAQQFQQQYQYNANYYKQA 133
            .:.::::.:|:|.||::.::..::  |....|...|                           .|
  Rat    52 FLQYDVLEALNMEKMMSAVSCWMENPGSSAGPAALE---------------------------SA 89

  Fly   134 NGGVYQYPPQQHPRHHPHHQQHHHQHHQIQQQQQHIMSINAQIAAQLRDKKVNFLLVEGFMIFNQ 198
            .|                                                 |..|::|||::||.
  Rat    90 QG-------------------------------------------------VPILIIEGFLLFNY 105

  Fly   199 PELLALCNIKYHFHLPYEKCFERRSKRTYDPPDVTGYFELCVWPHYEKNFSEYRDCK-DITFLNG 262
            ..|..:.|..|...:|||:|..|||.|.|:|||..|||:..|||.|.|:..|..... ||.:|:|
  Rat   106 KPLDTIWNRSYFLTVPYEECKRRRSTRVYEPPDPPGYFDGHVWPMYLKHRQEMNSITWDIVYLDG 170

  Fly   263 EIAKEKILAFVLHRI--------------VH--YFKERCE 286
            ..::|.:.:.|...:              ||  |.::.|:
  Rat   171 TRSEEDLFSQVYEDVKQELEKQNAVRLLEVHHVYSQDLCQ 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12016	NP_647805.1	NRK1	6..255	CDD:238982	63/250 (25%)
Nmrk1	XP_008758512.1	NRK1	5..158	CDD:238982	62/246 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351744
Domainoid	1	1.000	98	1.000	Domainoid score	I7008
eggNOG	1	0.900	-	-		E1_COG0572
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6787
Inparanoid	1	1.050	115	1.000	Inparanoid score	I4734
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002351
OrthoInspector	1	1.000	-	-		otm45777
orthoMCL	1	0.900	-	-		OOG6_103047
Panther	1	1.100	-	-	O	PTHR10285
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2461
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.750