DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12016 and MOCS2

DIOPT Version :9

Sequence 1:	NP_647805.1	Gene:	CG12016 / 38411	FlyBaseID:	FBgn0035436	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_004522.1	Gene:	MOCS2 / 4338	HGNCID:	7193	Length:	188	Species:	Homo sapiens

Alignment Length:	97	Identity:	19/97 - (19%)
Similarity:	33/97 - (34%)	Gaps:	26/97 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   218 CFERRSKRTYDPPDVTGYFELCVWPHYEKNFSEYRD-CKDITFLNGEIAKEKILAFVLHRIVHYF 281
            ||...:|....||.|    |...:....|:..|..: .||                    ::::.
Human    10 CFSLETKLPLSPPLV----EDSAFEPSRKDMDEVEEKSKD--------------------VINFT 50

  Fly   282 KERCEVPAPAPVVCPPQQKRFGMLYMGPSNNN 313
            .|:..|...:.:|..|...... |::|.:.||
Human    51 AEKLSVDEVSQLVISPLCGAIS-LFVGTTRNN 81

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12016	NP_647805.1	NRK1	6..255	CDD:238982	9/37 (24%)
MOCS2	NP_004522.1	MoaE	54..177	CDD:238385	7/29 (24%)
		Substrate binding. /evidence=ECO:0000255\|HAMAP-Rule:MF_03052	143..144
		Substrate binding. /evidence=ECO:0000255\|HAMAP-Rule:MF_03052	166..168
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R840
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.030