Protein Alignment CG12016 and NMRK2

DIOPT Version :9

• Sequence 1: NP_647805.1
• Gene: CG12016 / 38411
• FlyBaseID: FBgn0035436
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_001276046.1
• Gene: NMRK2 / 27231
• HGNCID: 17871
• Length: 235
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 75/293 - (25%)
• Similarity: 118/293 - (40%)
• Gaps: 93/293 - (31%)

  Fly     5 LVIGISGVTCGGKTTLAHSLHDYFKGLRGAPLWNSPYTIGEVRLISQDDYF-LPVEDKRHQRNEA 68
            |::||.|:|.||||||.:||      ||..|         ...:|.|||:| .|:...:.|  .|
Human     3 LIVGIGGMTNGGKTTLTNSL------LRALP---------NCCVIHQDDFFKAPLFQPQDQ--IA 50

  Fly    69 LNAINF---ELITSLDMAKMLNDIAHIIKGRHVAPEPQEHLVTYANFEHYAQQFQQQYQYNANYY 130
            :....|   :::.||||..||:.:
Human    51 VGEDGFKQWDVLESLDMEAMLDTV----------------------------------------- 74

  Fly   131 KQANGGVYQYPPQQHPRHHPHHQQHHHQHHQIQQQQQHIMSINAQIAAQLRDKKVNFLLVEGFMI 195
             ||    :...||:..|.|                         .::.|......:.||:|||::
Human    75 -QA----WLSSPQKFARAH-------------------------GVSVQPEASDTHILLLEGFLL 109

  Fly   196 FNQPELLALCNIKYHFHLPYEKCFERRSKRTYDPPDVTGYFELCVWPHYEKNFSEYR-DCKDITF 259
            ::...|:.|.:.:|...:|||:|..|||.|.|..||..|.|:..|||.|:|...|.. :..::.:
Human   110 YSYKPLVDLYSRRYFLTVPYEECKWRRSTRNYTVPDPPGLFDGHVWPMYQKYRQEMEANGVEVVY 174

  Fly   260 LNGEIAKEKILAFVLHRIVHYFKERCEVPAPAP 292
            |:|..::|::...||..|.:....|.:..||:|
Human   175 LDGMKSREELFREVLEDIQNSLLNRSQESAPSP 207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12016	NP_647805.1	NRK1	6..255	CDD:238982	64/253 (25%)
NMRK2	NP_001276046.1	NRK1	4..169	CDD:238982	64/252 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157778
Domainoid	1	1.000	95	1.000	Domainoid score	I7423
eggNOG	1	0.900	-	-		E1_COG0572
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	119	1.000	Inparanoid score	I4783
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002351
OrthoInspector	1	1.000	-	-		otm41655
orthoMCL	1	0.900	-	-		OOG6_103047
Panther	1	1.100	-	-	O	PTHR10285
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R840
SonicParanoid	1	1.000	-	-		X2461
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.780