Protein Alignment ZnT63C and SLC30A4

DIOPT Version :9

• Sequence 1: NP_001261364.1
• Gene: ZnT63C / 38407
• FlyBaseID: FBgn0035432
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_037441.2
• Gene: SLC30A4 / 7782
• HGNCID: 11015
• Length: 429
• Species: Homo sapiens
• Alignment Length: 342
• Identity: 96/342 - (28%)
• Similarity: 172/342 - (50%)
• Gaps: 57/342 - (16%)

  Fly     8 KCRLLSMMWLTAFFFFVEIIVGYVTNSMALVADSFHMLGDIAALVISFLSVKMSPKKWSKN-TFG 71
            |.||.....|...|...|::.||:.||:|::.|:.|||.|::|::::.|::.:|.|..:|. |||
Human   111 KARLTIAAVLYLLFMIGELVGGYIANSLAIMTDALHMLTDLSAIILTLLALWLSSKSPTKRFTFG 175

  Fly    72 WARAEVLGALVNAVFLVALCFSITIEACKRFIEEEPIHEPELLVIVGALGLLVNVIGLCLLYEHG 136
            :.|.|||.|:::.:.:..|...:..||.:|.|........::::|..|:|:.||||...||.:.|
Human   176 FHRLEVLSAMISVLLVYILMGFLLYEAVQRTIHMNYEINGDIMLITAAVGVAVNVIMGFLLNQSG 240

  Fly   137 GHHGHSH---------GGGLTRNHSRLTELANMDEGEDEQNDFAYEKQKEKAPVKKSSHGHSHDP 192
            ..|.|||         |.|..|||           |:|
Human   241 HRHSHSHSLPSNSPTRGSGCERNH-----------GQD--------------------------- 267

  Fly   193 GQMNMRGAFLHVLSDALGSIIVVISAVVV-WKTEWKYRYYMDPALSIVLVVLILHSVWPLLRESA 256
             .:.:|.||:|.|.|.:.|:.|:|:|.:: :|.|:|   ..||..:.|..:|:..:.:.::.::.
Human   268 -SLAVRAAFVHALGDLVQSVGVLIAAYIIRFKPEYK---IADPICTYVFSLLVAFTTFRIIWDTV 328

  Fly   257 LILLQTVPTHIQVDAIQKRLLEKVDGVLAVHEFHVWQLAGDRIIASAHIRC--RNLSEYMKIAEK 319
            :|:|:.||:|:.||.|::.|: |::.|.:|.:.::|.|...:..|..||:.  .:.|::.::..|
Human   329 VIILEGVPSHLNVDYIKEALM-KIEDVYSVEDLNIWSLTSGKSTAIVHIQLIPGSSSKWEEVQSK 392

  Fly   320 VKEFFHNE-GIHSTTIQ 335
            ......|. |::..|||
Human   393 ANHLLLNTFGMYRCTIQ 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT63C	NP_001261364.1	CzcD	10..339	CDD:224151	95/340 (28%)
		Cation_efflux	21..260	CDD:279834	69/249 (28%)
SLC30A4	NP_037441.2	CDF	123..413	CDD:273544	92/330 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1230
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D820567at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820