Protein Alignment ZnT63C and Slc30a7

DIOPT Version :9

• Sequence 1: NP_001261364.1
• Gene: ZnT63C / 38407
• FlyBaseID: FBgn0035432
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_075703.1
• Gene: Slc30a7 / 66500
• MGIID: 1913750
• Length: 378
• Species: Mus musculus
• Alignment Length: 358
• Identity: 112/358 - (31%)
• Similarity: 179/358 - (50%)
• Gaps: 35/358 - (9%)

  Fly     5 SGKKCR-LLSMMWLTAFFFFVEIIVGYVTNSMALVADSFHMLGDIAALVISFLSVKMSPKKWSKN 68
            |.|..| |...:.|...|.|||::.|..:|.:.|::|||||..|..|::....:..:|  ||..|
Mouse    31 SDKTSRNLFFFLCLNLSFAFVELLYGIWSNCLGLISDSFHMFFDSTAILAGLAASVIS--KWRDN 93

  Fly    69 ---TFGWARAEVLGALVNAVFLVALCFSITIEACKRFIEEEPIHEPELLVIVGALGLLVNVIGLC 130
               ::|:.|||||...||.:||:...|.|..|..:|.:....:|. |.|::|..||.:||::|:
Mouse    94 DAFSYGYVRAEVLAGFVNGLFLIFTAFFIFSEGVERALAPPDVHH-ERLLLVSILGFVVNLVGI- 156

  Fly   131 LLYEHGGHHGHSHGGGLTRNHSRLTELANMDEGEDE-------QNDFAYEKQKEKAPVKKSSHG- 187
            .::.||| ||||||.|...:||......:...|.::       ::..|:....:.|    ..||
Mouse   157 FVFNHGG-HGHSHGSGHGHSHSLFNGALDHSHGHEDHCHSHEAKHGAAHSHDHDHA----HGHGH 216

  Fly   188 -HSHD---------PGQMNMRGAFLHVLSDALGSIIVVISAVVVWKTEWKYRYYMDPALSIVLVV 242
             ||||         |.:..::|.|||:|:|.||||.|:.||:::....   ....||..||::.:
Mouse   217 LHSHDGPSFKATAGPSRQILQGVFLHILADTLGSIGVIASAIMMQNFG---LMIADPICSILIAI 278

  Fly   243 LILHSVWPLLRESALILLQTVPTHIQVDAIQ-KRLLEKVDGVLAVHEFHVWQLAGDRIIASAHIR 306
            ||:.||.||||||..||:|..|..::....| .:.::::.||..:.|.|.|.|..|..:.:..:.
Mouse   279 LIVVSVIPLLRESVGILMQRTPPSLENTLPQCYQRVQQLQGVYNLQEQHFWTLCSDVYVGTLKLV 343

  Fly   307 CRNLSEYMKIAEKVKEFFHNEGIHSTTIQPEFS 339
            ....::...|..:....|...|:....:|.:|:
Mouse   344 VAPDADARWILSQTHNIFTQAGVRQLYVQIDFA 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT63C	NP_001261364.1	CzcD	10..339	CDD:224151	109/351 (31%)
		Cation_efflux	21..260	CDD:279834	91/259 (35%)
Slc30a7	NP_075703.1	CzcD	31..376	CDD:224151	111/356 (31%)
		Cation_efflux	48..296	CDD:279834	91/259 (35%)
		His-rich loop	161..220		18/63 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	186..224		9/41 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1230
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG51881
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2014
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.850