Protein Alignment ZnT63C and slc30a5

DIOPT Version :9

• Sequence 1: NP_001261364.1
• Gene: ZnT63C / 38407
• FlyBaseID: FBgn0035432
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_001015911.1
• Gene: slc30a5 / 548665
• XenbaseID: XB-GENE-962722
• Length: 777
• Species: Xenopus tropicalis
• Alignment Length: 385
• Identity: 109/385 - (28%)
• Similarity: 188/385 - (48%)
• Gaps: 62/385 - (16%)

  Fly     1 MAKYSGKKCRLLSMMWLTAFFFFVEIIVGYVTNSMALVADSFHMLGDIAALVISFLSVKMSPKKW 65
            :.:|..:  ::...:.|...|.||||..|..|||:.|::|.||||.|.:|||:..::..|:  :|
 Frog   407 LEEYDSR--QIFYFLCLNLAFTFVEIFYGVWTNSLGLLSDGFHMLFDCSALVMGLIAALMT--RW 467

  Fly    66 SKN---TFGWARAEVLGALVNAVFLVALCFSITIEACKRFIEEEPIHEPELLVIVGALGLLVNVI 127
            ...   ::|:.|.|:|...:|.:|||.:.|.:.|||..| |.:.|....::|..|...||:||::
 Frog   468 KATRIFSYGYGRVEILSGFINGLFLVVIAFFVFIEAVAR-IYDPPDINTDMLTPVSVGGLIVNLV 531

  Fly   128 GLCLL---------------YEHG-GHHGHSHGGGLTRNHSRLTELANMDEGEDEQNDFAYEKQK 176
            |:|..               ::|| .||||.|..|....||      :.|.|.:..:
 Frog   532 GICAFSHAHSHGAARGGCPSHDHGHSHHGHGHSHGHNHGHS------HSDHGHNHGH-------- 582

  Fly   177 EKAPVKKSSHGHSHDPG----QMNMRGAFLHVLSDALGSIIVVISAVVVWKTEWKYRYYMDPALS 237
                  ..:|||||...    ..||||.|.|||:|.|||:.|::|.:::.:..|   ...||..|
 Frog   583 ------THNHGHSHGSAGVGMNANMRGVFSHVLADTLGSVGVIVSTILIRQFGW---LIADPLCS 638

  Fly   238 IVLVVLILHSVWPLLRESALILLQTVPTHIQVD---AIQKRLLEKVDGVLAVHEFHVWQLAGDRI 299
            :.:.|||..||.|||:::..::|..:|...:..   |::|  :..:||:::..:.|.|:.:...:
 Frog   639 LFIAVLIFGSVLPLLKDACQVILLRIPQETEKGINIALEK--ISNLDGLISYRDPHFWRHSASLV 701

  Fly   300 IASAHIRCRNLSEYMKIAEKVKEFFHNEGIHSTTIQPE----FSEIEGCNMSDGTSSINI 355
            ..:.|::..:.....:|.::|.....:.|:::.|:|.|    |..:.|  :|.|...:.|
 Frog   702 AGTIHVQVMSDVVEQRIIQQVTSLLKDAGVNNLTVQVEKEAYFQHMSG--LSTGFQDVLI 759

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT63C	NP_001261364.1	CzcD	10..339	CDD:224151	103/358 (29%)
		Cation_efflux	21..260	CDD:279834	87/261 (33%)
slc30a5	NP_001015911.1	CzcD	411..741	CDD:224151	103/359 (29%)
		Cation_efflux	424..661	CDD:279834	87/262 (33%)
		His-rich loop	538..586		12/67 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	547..593		17/65 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2014
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940