Protein Alignment ZnT63C and slc30a5

DIOPT Version :10

• Sequence 1: NP_001261364.1
• Gene: ZnT63C / 38407
• FlyBaseID: FBgn0035432
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_001002322.1
• Gene: slc30a5 / 436594
• ZFINID: ZDB-GENE-040718-6
• Length: 775
• Species: Danio rerio
• Alignment Length: 391
• Identity: 111/391 - (28%)
• Similarity: 188/391 - (48%)
• Gaps: 88/391 - (22%)

  Fly     1 MAKYSGKKCRLLSMMWLTAFFFFVEIIVGYVTNSMALVADSFHMLGDIAALVISFLSVKMSPKKW 65
            :.:|..:  ::...:.|...|.|||:..|..|||:.|::|.||||.|.:|||:...:..|:  :|
Zfish   407 LEEYDSR--QIFYFLCLNLAFTFVELFYGVWTNSLGLISDGFHMLFDCSALVLGLFAALMT--RW 467

  Fly    66 SKN---TFGWARAEVLGALVNAVFLVALCFSITIEACKRFIEEEPIHEPELLVIVGALGLLVNVI 127
            ...   ::|:.|.|:|...:|.:||:.:.|.:.:|:..|.::...|: .::|..|...||:||::
Zfish   468 KATRIYSYGYGRVEILSGFINGLFLMVIAFFVFVESVTRLVDPPNIN-TDMLTPVSVGGLIVNLV 531

  Fly   128 GLCLL---------------YEHG------GH---------HGHSHGGGLTRNHSRLTELANMDE 162
            |:|..               ::||      ||         |||||||   ..||.
Zfish   532 GICAFSHAHSHGASKGSCSGHDHGHSHHGHGHSSMEHSHGGHGHSHGG---HGHSH--------- 584

  Fly   163 GEDEQNDFAYEKQKEKAPVKKSSHGHSHDPGQM--NMRGAFLHVLSDALGSIIVVISAVVVWKTE 225
                                  .|||||..|.|  ||||.|||||:|.|||:.|:||.:::.:..
Zfish   585 ----------------------GHGHSHSSGGMNANMRGVFLHVLADTLGSVGVIISTILIRQFG 627

  Fly   226 WKYRYYMDPALSIVLVVLILHSVWPLLRESALILLQTVPTHIQVD---AIQKRLLEKVDGVLAVH 287
            |   ...||..|:.:..||..||.|||:::..:||..:|...:.:   |::|  ::|::|||:..
Zfish   628 W---LIADPICSLFISTLIFLSVIPLLKDACEVLLLRMPPQHEKELNFALEK--IQKIEGVLSYR 687

  Fly   288 EFHVWQLAGDRIIASAHIRCRNLSEYMKIAEKVKEFFHNEGIHSTTIQPE----FSEIEGCNMSD 348
            :.|.|:.:...|..:.|::..:.....::.::|.....:.|:::.|||.|    |..:.|  :|.
Zfish   688 DPHFWRHSASVIAGTIHLQLMSDVVEQRVIQQVSAVLKDAGVNNLTIQLEKEAYFQHMSG--LSS 750

  Fly   349 G 349
            |
Zfish   751 G 751

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT63C	NP_001261364.1	CzcD	10..340	CDD:440843	107/371 (29%)
slc30a5	NP_001002322.1	CzcD	419..740	CDD:440843	106/362 (29%)
		His-rich loop, required for zinc transport. /evidence=ECO:0000250|UniProtKB:Q8TAD4	538..584		12/48 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	547..592		18/78 (23%)