Protein Alignment ZnT63C and Slc30a4

DIOPT Version :10

• Sequence 1: NP_001261364.1
• Gene: ZnT63C / 38407
• FlyBaseID: FBgn0035432
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_035904.2
• Gene: Slc30a4 / 22785
• MGIID: 1345282
• Length: 430
• Species: Mus musculus
• Alignment Length: 333
• Identity: 93/333 - (27%)
• Similarity: 174/333 - (52%)
• Gaps: 38/333 - (11%)

  Fly     8 KCRLLSMMWLTAFFFFVEIIVGYVTNSMALVADSFHMLGDIAALVISFLSVKMSPKKWSKN-TFG 71
            |.||.....|...|...|::.||:.||:|::.|:.|||.|::|::::.|::.:|.|..::. |||
Mouse   111 KTRLTIAAVLYLLFMIGELVGGYMANSLAIMTDALHMLTDLSAIILTLLALWLSSKSPTRRFTFG 175

  Fly    72 WARAEVLGALVNAVFLVALCFSITIEACKRFIEEEPIHEPELLVIVGALGLLVNVIGLCLLYEHG 136
            :.|.|||.|:::.:.:..|...:..||.:|.|........::::|..|:|:.||||...||.:.|
Mouse   176 FHRLEVLSAMISVMLVYVLMGFLLYEAVQRTIHMNYEINGDVMLITAAVGVAVNVIMGFLLNQSG 240

  Fly   137 GHHGHSHGGGLTRNHSRLTELANMDEGEDEQNDFAYEKQKEKAPVKKSSHGHSHDPGQMNMRGAF 201
            .||.|:|...|..|...:.                             |.||:|....:.:|.||
Mouse   241 HHHSHAHSHSLPSNSPSMV-----------------------------SSGHNHGQDSLAVRAAF 276

  Fly   202 LHVLSDALGSIIVVISAVVV-WKTEWKYRYYMDPALSIVLVVLILHSVWPLLRESALILLQTVPT 265
            :|.|.|.:.|:.|:|:|.:: :|.|:|   ..||..:.:..:|:..:.:.::.::.:|:|:.||:
Mouse   277 VHALGDLVQSVGVLIAAYIIRFKPEYK---IADPICTYIFSLLVAFTTFRIIWDTVVIILEGVPS 338

  Fly   266 HIQVDAIQKRLLEKVDGVLAVHEFHVWQLAGDRIIASAHIRC--RNLSEYMKIAEKVKEFFHNE- 327
            |:.||.|::.|: |::.|.:|.:.::|.|...:..|..|::.  .:.|::.::..|.|....|.
Mouse   339 HLNVDYIKESLM-KIEDVYSVEDLNIWSLTSGKSTAIVHMQLIPGSSSKWEEVQSKAKHLLLNTF 402

  Fly   328 GIHSTTIQ 335
            |::..|||
Mouse   403 GMYKCTIQ 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT63C	NP_001261364.1	CzcD	10..340	CDD:440843	92/331 (28%)
Slc30a4	NP_035904.2	CDF	123..414	CDD:273544	89/321 (28%)
		Zinc binding. /evidence=ECO:0000250|UniProtKB:O55174	240..265		10/53 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	245..264		6/47 (13%)