DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ZnT63C and toc-1

DIOPT Version :9

Sequence 1:	NP_001261364.1	Gene:	ZnT63C / 38407	FlyBaseID:	FBgn0035432	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_001367624.1	Gene:	toc-1 / 175728	WormBaseID:	WBGene00006590	Length:	446	Species:	Caenorhabditis elegans

Alignment Length:	358	Identity:	73/358 - (20%)
Similarity:	122/358 - (34%)	Gaps:	128/358 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LLSMMWLTAFFFFVEIIVGYVTNSMALVADSFHMLGDIAALVISFLSVKMSPKKWSKNTFGWARA 75
            |:|.:|:|.|.|                          .:...|..|:.::.|...|.::|.||.
Worm    63 LMSTLWITIFSF--------------------------CSQFASLYSMSITEKPTHKFSYGLARV 101

  Fly    76 EVLGALVNAVF---LVALCFSITIEACKRFIEEEPIHEPELLVIVGALGLLVNVIGLCLLYEH-- 135
            .||     |||   ::|..|||       |:.:|.                         :||
Worm   102 PVL-----AVFSTTVLAQLFSI-------FLSKES-------------------------FEHLL 129

  Fly   136 -GGHHGHSHGGGLTRNHSRLTELANMDEGEDEQNDFAY--EKQKEKAPVKKSSHGHSHDPGQMNM 197
             ..||| ||.......|.           .:|...:.|  ........:..|::...:.|
Worm   130 SPDHHG-SHDASAAHEHE-----------VEEIGGWPYFVGSAASSVALLLSAYALKNQP----- 177

  Fly   198 RGAFLHVLSDALGSII----VVISAVVVWK-----------------------------TEWKYR 229
               |.|||..|..|.:    ..:|..|.|.                             ..:|:.
Worm   178 ---FQHVLQSATASSLQEHAADLSHAVCWVIPGLSRLLLPRINSMVLLALTTTGLNLLCEHFKHD 239

  Fly   230 Y-YMDPALSIVLVVLILHSVWPLLRESALILLQTVPTHIQVDAIQKRLLE--KVDGVLAVHEFHV 291
            : :.||...::|.|.:..:::||...:.:|||||.|.|: ::.|.:.:.|  .:||||.:.....
Worm   240 FAWADPVCCLLLSVAVFSTMYPLSTYTGMILLQTTPPHL-INQIDRCISEASHIDGVLELKSGRF 303

  Fly   292 WQLAGDRIIASAHIRCRNLSEYMKIAEKVKEFF 324
            |||..:.::.:..:|.|..::...:...|.|.|
Worm   304 WQLDFNSLVGTVDVRVRRDADEQNVLAHVTEKF 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ZnT63C	NP_001261364.1	CzcD	10..339	CDD:224151	73/358 (20%)
ZnT63C	NP_001261364.1	Cation_efflux	21..260	CDD:279834	48/280 (17%)
toc-1	NP_001367624.1	Cation_efflux	45..271	CDD:396224	53/290 (18%)
toc-1	NP_001367624.1	ureE	<378..441	CDD:237323
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910