DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14968 and numb

DIOPT Version :9

Sequence 1:	NP_647800.1	Gene:	CG14968 / 38406	FlyBaseID:	FBgn0035431	Length:	199	Species:	Drosophila melanogaster
Sequence 2:	NP_001260291.1	Gene:	numb / 34263	FlyBaseID:	FBgn0002973	Length:	556	Species:	Drosophila melanogaster

Alignment Length:	198	Identity:	49/198 - (24%)
Similarity:	73/198 - (36%)	Gaps:	58/198 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 VEDLPITFKVKYIGS-EV--ARGLW----GIKY----TRRPVDIMVGVAKNLPPNKVLPNCELKV 70
            |.....:|.|||:|. ||  :||:.    .:|.    .||||       :.|          |.|
  Fly    76 VRSATCSFSVKYLGCVEVFESRGMQVCEEALKVLRQSRRRPV-------RGL----------LHV 123

  Fly    71 STDGVQLEIISPKASINHWSYPIDTISYGVQDLVYTRVFAMIVVKDESSPHPFEVHAFVC--DSR 133
            |.||:::.....|..|  ....|:.:|:...|..:.|.|:.|.  .:.:...:..|.|:.  ||
  Fly   124 SGDGLRVVDDETKGLI--VDQTIEKVSFCAPDRNHERGFSYIC--RDGTTRRWMCHGFLACKDS- 183

  Fly   134 AMARKLTFALAAAF----QDYSRRVKEATGEEEGEATPSDTITPTRHKFAIDLRTPEEIQAGELE 194
              ..:|:.|:..||    :...||.||. |......|.:.|.|.|                |...
  Fly   184 --GERLSHAVGCAFAVCLERKQRRDKEC-GVTMTFDTKNSTFTRT----------------GSFR 229

  Fly   195 QET 197
            |:|
  Fly   230 QQT 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14968	NP_647800.1	PTB_LDLRAP_insect-like	23..147	CDD:269982	34/136 (25%)
numb	NP_001260291.1	PTB_Numb	67..201	CDD:241298	37/148 (25%)
numb	NP_001260291.1	NumbF	269..374	CDD:283874
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11232
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010