Protein Alignment CG12009 and thw

DIOPT Version :10

• Sequence 1: NP_647799.1
• Gene: CG12009 / 38405
• FlyBaseID: FBgn0035430
• Length: 905
• Species: Drosophila melanogaster
• Sequence 2: NP_001097699.2
• Gene: thw / 40868
• FlyBaseID: FBgn0037487
• Length: 1137
• Species: Drosophila melanogaster
• Alignment Length: 1205
• Identity: 233/1205 - (19%)
• Similarity: 373/1205 - (30%)
• Gaps: 438/1205 - (36%)

  Fly     5 LCLLLLLTATCSAGPLSAHQKRKAPVT-----------REEPVPAEVEMPE-----QTETEDEEA 53
            ||.|::|..   .|..||..|.:.|..           .||...|.....|     :....||:.
  Fly    22 LCALIVLVI---LGYTSAESKYRTPARILAKQTGATQFEEERYEAHTNCNEHKHHLKKRASDEDV 83

  Fly    54 PAEAASMGTLTLPSNATSIRSDI-TDNFSCVNKTYGYYADVENDCQIFHVCLPVTYADGRENTFR 117
            ..| ...|.:..|.....|...| ..:|||.:...||:||:|.|||:||:|     .:||    :
  Fly    84 DYE-VYQGVVGRPGIDFPIYPRIPKTSFSCRSYGNGYFADMETDCQVFHIC-----EEGR----K 138

  Fly   118 WSFICPEETIFSQESFTCMRRED--MTIECEDSSRYYELNGNF---------------------G 159
            .||:||..|||.|...||    |  ..:.|..||.||..:...                     |
  Fly   139 ISFLCPNGTIFQQSELTC----DWWFKVNCLGSSGYYAESAEILNKQRVHRVRPSVPVQGFNIVG 199

  Fly   160 GPAEEESKPTPVESE--------EPEK--EESEPEPEPVES------------------------ 190
            |....:.|.|||..:        .|::  :.:|..|..|||
  Fly   200 GGLNIKPKVTPVAGQGRSAAPRANPDRRIDSTEDVPASVESVDFDDVSGEKQRKVLPSIDNNSND 264

  Fly   191 -EPEIPAE----------------------PEVQTAKPMK---PVKAQ----------------- 212
             |.:|.||                      .::...||.:   ||..|
  Fly   265 QESQITAESSSFVSGSGKRRTNKESNPNRNDDITVLKPARLRTPVATQERGVSTERARNGQRGQH 329

  Fly   213 -------------KPKPNRRKPQPQ-------RKVP-----------AVVTAAPEVEAIP--EPS 244
                         :|.|.:.|.:|:       |.||           :.|......::.|  .|:
  Fly   330 RYSGSEEHSKERERPTPGQSKEKPEFFEAHSTRSVPQTTAHYSTGSHSTVRRLEPSKSTPFYTPT 394

  Fly   245 APVEMEPKPLK----------------PQRFTSR------PHQERPQVKRPAIAAPPMRNELFNG 287
            .|..::.|..:                |.||.|.      .....|:||..|.|:..:.:..
  Fly   395 VPSLVKSKSTEGKLNYIKGGHVATTPNPHRFGSASSGIFIESSVAPKVKPTASASIELDSTF--- 456

  Fly   288 IRKRPAIFN-------------KPPTTVKPVEEVVENEPAVTEAVVQLSEPQPTLKLQTLFAEPE 339
               :|.|..             :||:......:.:...|:.:.|                .:.|.
  Fly   457 ---KPVIIGMRHHYDVASSGEFRPPSKSTESRDYLPTTPSPSAA----------------SSGPT 502

  Fly   340 VIPVEVQEPEVQ----ASEPAVTFVQPEPVVEEVVPSKVE--------IDTRIEDVKPIEAIEEI 392
            .:|:..:.|.|.    |.|..:.|. |.||.||.|...|:        :..:.|||: :.|....
  Fly   503 YLPMSGKSPRVNTGGAAGEDVLLFA-PNPVKEESVFRNVQDMLKTMNLLKDQFEDVE-LNAAAAA 565

  Fly   393 PA-VIVESLDQSRP-----------QEMQEEAKITEEEAKPEEEPKPEEEVKLEEELKSEEAAKP 445
            || |.:|....|.|           ||..|......::.|.|:..|...:.||        :.||
  Fly   566 PARVGLEIPPSSGPDALVSFAKYFAQEHNETINSLSKKDKSEKVDKTGVQTKL--------SVKP 622

  Fly   446 EV-ELKPQEIQA----QEEPEVPAKVEEIIEANPEEIK----SEPAIMEVSNSHEEPLVNLEALE 501
            .: .:||.:..|    .|.|  ||     |..|.::||    |:..:.:.|        ||..|:
  Fly   623 PLPTIKPSDTTALLTTSENP--PA-----ISDNADDIKKSLLSDTTVKKYS--------NLFGLK 672

  Fly   502 AAKPADAPESMPATPEMEQHSPLVEEILDNTNDGEAQESLGGFKPVDPVMAA-----------EA 555
            :|:...|.|           |.:...:|.|..:|...|:...::....:.:.           |.
  Fly   673 SAQGRGAGE-----------SDISSGLLSNQTNGTQSEAGSKYQQYPQIGSTGSTIGALAEKPET 726

  Fly   556 EQLITDFLNTLKKNEEKPETDLAE--------------SILPVNNTDVSI---EEAK--LPEPEI 601
            .::...|.|.|....:.|.|..||              :..||..||.|:   ..||  ||...:
  Fly   727 RKIAQIFSNALSSYLDNPATFRAELAARARPTEPPSTPNFKPVTTTDPSLFSDGTAKYYLPTKGL 791

  Fly   602 VDKNASVEEQLLEETEDK--------KSHKTEMMQDSPIINIMQVQHMPMDYRIPVRVIPVEVQP 658
            .|........:..|...|        .|..||:.:.|        .:..:::.
  Fly   792 PDATTPTPNSIAAEINHKFDSTLAPEFSTTTELYEGS--------TNRGLEFS------------ 836

  Fly   659 VPAISEASEVAKESAPEVVSESSLEEAKESAAEEAKESIPEEVVDT-----APEEVKQ----IPN 714
                .|.|..:::|..|.:.:...:...:|..:..|::.|:::|.|     .|..:|.    :..
  Fly   837 ----GELSPPSQDSGEEFLQQQQTQSFVKSRNDLLKDARPQKLVTTHKPTEHPWALKSQTDFLDP 897

  Fly   715 VEIQESPMEEPKES------------SPEEIKESTP-------EEI-------KETAPETEVELV 753
            :.|.:..|:|.:.|            ||...:.:||       |:|       ::..|.:.....
  Fly   898 LTINDGLMKEQRTSTSSSTTSTSTTASPFAYRVTTPTPSRYEWEDIFRSYDIPRDALPSSSGLQR 962

  Fly   754 VA-------PDQTAFH--------DDDAQESLVTAAYMPSIED----------------IVEL-- 785
            :|       .:|.|.|        :.|.|...:....:.:.:|                ::::
  Fly   963 IANKLFGGLNEQEALHLRNVMAKAEHDRQVLSLLLLLIQTCDDHNGKALERSRKHLLNALIDIDS 1027

  Fly   786 --------VKERLDQTPKKDQMAPMELILTPGGAEPMSLVQSTPEQLEPESQPTEEAASTAGQEE 842
                    .::||..|..:   .|:......|.|.......:||........||.........||
  Fly  1028 KTHAGGKTSRQRLTTTTNR---IPVTTFRRGGAAAAEYFTSTTPGYTTTTDLPTTTGLGAGSYEE 1089

  Fly   843 EVILPIYKRVSTAEPAMSKVQTLPVTVSKVDTEAL 877
            .....|  ||...|.|.:  .|.|:.....|..||
  Fly  1090 TTKFEI--RVEDLEEATT--TTAPLLEVNSDRRAL 1120

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12009	NP_647799.1	CBM_14	82..145	CDD:426342	25/64 (39%)
		PRK10263	<203..>357	CDD:236669	38/245 (16%)
thw	NP_001097699.2	CBM_14	112..164	CDD:426342	25/64 (39%)