DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17746 and si:ch211-15p9.2

DIOPT Version :9

Sequence 1:	NP_647794.1	Gene:	CG17746 / 38400	FlyBaseID:	FBgn0035425	Length:	371	Species:	Drosophila melanogaster
Sequence 2:	NP_001038455.2	Gene:	si:ch211-15p9.2 / 562650	ZFINID:	ZDB-GENE-060503-577	Length:	505	Species:	Danio rerio

Alignment Length:	432	Identity:	95/432 - (21%)
Similarity:	147/432 - (34%)	Gaps:	160/432 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 TAKESAYCQNA-AYRVGSSCMQGWRINMEDSHTHILSLPDDPGAA---------FFAVYDGHGGA 64
            |.|.|.|.... ||   :.|::|:..|:..|:    |..:|..:|         .|.|:|||.|:
Zfish    72 TLKASEYSLKVNAY---NGCVKGFDSNILPSN----SPSEDRRSAATCLQSRGMLFGVFDGHAGS 129

  Fly    65 TVAQYAGKHLHKYVL------------------KRP-------EYNDNIEQALQQGFL------- 97
            ..||...:.|..|:.                  :||       ..:.|..|:...|.|
Zfish   130 ACAQAVSERLFYYIALSLLPLRTLMEIEAAVESERPVLPVLQWHKHPNDYQSTDSGKLYFSSLRT 194

  Fly    98 ----DIDYVMLRNKTCGDQ-----------------------------------MAGSTAVVVLV 123
                .||  :..|:.|..|                                   ::|.||.|..|
Zfish   195 YWQERID--LQENEDCDTQGAFRNAFKRLDNDISLEAQVDIGVPLAHFTPLRVALSGCTACVAYV 257

  Fly   124 KDNKLYCANAGDSRAIACV---NGQLEVLSL--DHKPNNEAESKRII------QGGGWVEFNRVN 177
            ..:.||.||.|||||:..|   :|:....::  ||...|..|.||::      :....|:.:|:.
Zfish   258 DQDDLYIANLGDSRAVLGVQQGDGKWSAFTITNDHNAQNPNEMKRVLSEHPACEQKTVVKHDRLL 322

  Fly   178 GNLALSRALGDYVFKHENK--------KPEDQI-----------------VTAFPDVETRKIMDD 217
            |.|...||.||..||..::        :||..|                 :||.|::...|:...
Zfish   323 GLLIPFRAFGDMKFKWSSELLNRIYEARPELLIGNENAKMLPANYHTPPYLTAEPEITYHKLRPQ 387

  Fly   218 WEFIVLACDGIWDVMSNAEVLEFCRTRIG--------MGMF----------------------PE 252
            .:|::|..||:|::|....|::.....:.        .||:                      .|
Zfish   388 DKFLILGTDGLWELMHRQTVVQVIGEHLSGIEWKKPVSGMYFTVGQMHRLLRERKRRALSAREDE 452

  Fly   253 EICEELMNHCLAPDCQMGGLGGDNMTVVLVCLLH--GRPYSD 292
            .....|:.|.|..| ..|.:..|.:..:| ||..  .|.|.|
Zfish   453 NSATHLIRHALGSD-GSGTIEHDRIAKML-CLPQDLARMYRD 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17746	NP_647794.1	PP2Cc	22..284	CDD:238083	85/407 (21%)
si:ch211-15p9.2	NP_001038455.2	PP2Cc	89..501	CDD:238083	88/412 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810