Protein Alignment CG17746 and PPM1A

DIOPT Version :9

• Sequence 1: NP_647794.1
• Gene: CG17746 / 38400
• FlyBaseID: FBgn0035425
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: XP_016876870.1
• Gene: PPM1A / 5494
• HGNCID: 9275
• Length: 459
• Species: Homo sapiens
• Alignment Length: 363
• Identity: 131/363 - (36%)
• Similarity: 193/363 - (53%)
• Gaps: 48/363 - (13%)

  Fly     1 MGQTLSEPVTAKESAYCQNAAYRVGSSCMQGWRINMEDSHTHILSLPDD-PGAAFFAVYDGHGGA 64
            ||..|.:|...|.:|..|....|.|.|.|||||:.|||:||.::.||.. ...:||||||||.|:
Human    78 MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYDGHAGS 142

  Fly    65 TVAQYAGKHLHKYVLKRPEYN--------DNIEQALQQGFLDIDYVM--LRNKTCGDQMAGSTAV 119
            .||:|..:||..::....::.        :|::..::.|||:||..|  :..|..|...:|||||
Human   143 QVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKHGADRSGSTAV 207

  Fly   120 VVLVKDNKLYCANAGDSRAIACVNGQLEVLSLDHKPNNEAESKRIIQGGGWVEFNRVNGNLALSR 184
            .||:.....|..|.||||.:.|.|.::...:.||||:|..|.:||...||.|...||||:||:||
Human   208 GVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVMIQRVNGSLAVSR 272

  Fly   185 ALGDYVFK--HENKKPEDQIVTAFPDV-ETRKIMDDWEFIVLACDGIWDVMSNAEVLEFCRTRIG 246
            ||||:.:|  | .|.|.:|:|:..|:| :..:..:|.:||:||||||||||.|.|:.:|.|:|:.
Human   273 ALGDFDYKCVH-GKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRSRLE 336

  Fly   247 MGMFPEEICEELMNHCLAPDCQMGGLGGDNMTVVLVCLLHGRPYSDLIARCRNGSQATNNDQEEA 311
            :....|::|.|:::.||....:      |||:|:|:|.                    .|..:.:
Human   337 VTDDLEKVCNEVVDTCLYKGSR------DNMSVILICF--------------------PNAPKVS 375

  Fly   312 GDATKDEVAKDEAEAETDTETETQTKPCQKQSNSGPMD 349
            .:|.|       .|||.|...|.:.:...|:...|..|
Human   376 PEAVK-------KEAELDKYLECRVEEIIKKQGEGVPD 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17746	NP_647794.1	PP2Cc	22..284	CDD:238083	112/275 (41%)
PPM1A	XP_016876870.1	PP2Cc	100..368	CDD:238083	112/274 (41%)
		PP2C_C	362..437	CDD:285117	14/72 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53745
OrthoDB	1	1.010	-	-		D262211at33208
OrthoFinder	1	1.000	-	-		FOG0000692
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100270
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R955
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.760