DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17746 and ppm-1.A

DIOPT Version :9

Sequence 1:	NP_647794.1	Gene:	CG17746 / 38400	FlyBaseID:	FBgn0035425	Length:	371	Species:	Drosophila melanogaster
Sequence 2:	NP_001023842.1	Gene:	ppm-1.A / 179469	WormBaseID:	WBGene00006460	Length:	468	Species:	Caenorhabditis elegans

Alignment Length:	394	Identity:	130/394 - (32%)
Similarity:	195/394 - (49%)	Gaps:	71/394 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGQTLSEPVTAKESAYCQNAAYRVGSSCMQGWRINMEDSH-THILSLPDDP--GAAFFAVYDGHG 62
            ||..|.:|.|.|.:.:.:....|.|.|.||||||.||||| ...:.....|  ..:||||:|||.
Worm    84 MGAFLDKPKTDKTNVHGEGNGIRYGMSSMQGWRICMEDSHIAEAIMSQSSPYKDWSFFAVFDGHA 148

  Fly    63 GATVAQYAGKHLHKYVLKRPEYNDN------------------IEQALQQGFLDIDYVMLRNKTC 109
            |..:|..|...|.::::...|:.:.                  :|:.:::|||..|.:   :||.
Worm   149 GHHIANRASSQLLEHLISSEEFREMTKTLEENNGVLTDSTLKLLEKGIKKGFLSFDEI---SKTS 210

  Fly   110 GD-QMAGSTAVVVLVKDNKLYCANAGDSRAIACVNGQLEVLSL-DHKPNNEAESKRIIQGGGWVE 172
            .| ..:|.|||..:|........|.|||||:  |.|:.|:... ||||..|.|.|||...||.|.
Worm   211 NDISKSGCTAVCAIVTPTHFIIGNLGDSRAV--VAGKNEIFGTEDHKPYLEKERKRIEGAGGSVM 273

  Fly   173 FNRVNGNLALSRALGDYVFKHENKKPED-QIVTAFPDVETR-KIMDDWEFIVLACDGIWDVMSNA 235
            ..|:||:||:|||.|||.:|.:.:.|.| |:|:..|||..| :.:::.:|:|:|||||:|||:|.
Worm   274 IQRINGSLAVSRAFGDYEYKDDPRLPADQQLVSPEPDVYIRERNLENDQFMVVACDGIYDVMTNE 338

  Fly   236 EVLEFCRTRIGMGMFPEEICEELMNHCLAPDCQMGGLGGDNMTVVLVCLLHGRPYSDLIARCRNG 300
            |:.||.:.|:.:.....|:|:::::.||....:      ||||:|:||.              ..
Worm   339 ELAEFVKDRLSVHSDLREVCDDVLDECLVKGSR------DNMTMVVVCF--------------PA 383

  Fly   301 SQATNNDQEEAGDATKDEVAK------DEAEAETDTETETQTKPCQKQSNSGPMDDEVKMASHLN 359
            :...|..::||.:|....|..      |||.|..|.:.|               :|.|.:.|.|:
Worm   384 APEVNIHRKEAEEAWVSRVKTVINQFLDEAVAAEDFKQE---------------EDMVTLKSILD 433

  Fly   360 KMAA 363
            |:.|
Worm   434 KVTA 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17746	NP_647794.1	PP2Cc	22..284	CDD:238083	106/286 (37%)
ppm-1.A	NP_001023842.1	PP2C	105..374	CDD:366121	101/279 (36%)
ppm-1.A	NP_001023842.1	PP2C_C	375..>412	CDD:392186	9/50 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53745
OrthoDB	1	1.010	-	-		D262211at33208
OrthoFinder	1	1.000	-	-		FOG0000692
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100270
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R955
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.860