DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17746 and PPM1K

DIOPT Version :9

Sequence 1:NP_647794.1 Gene:CG17746 / 38400 FlyBaseID:FBgn0035425 Length:371 Species:Drosophila melanogaster
Sequence 2:NP_689755.3 Gene:PPM1K / 152926 HGNCID:25415 Length:372 Species:Homo sapiens


Alignment Length:283 Identity:93/283 - (32%)
Similarity:132/283 - (46%) Gaps:57/283 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    24 VGSSCMQGWRINMEDSHTHILSLPDDPGAAFFAVYDGHGGATVAQYAGKHLHKYVLKRPEYNDNI 88
            ||.:...|.|...|| ......|.|:  ..:|||||||||...|.:...|:.|.::.......|:
Human    95 VGCASQIGKRKENED-RFDFAQLTDE--VLYFAVYDGHGGPAAADFCHTHMEKCIMDLLPKEKNL 156

  Fly    89 EQALQQGFLDIDYVMLRN-KTCGDQ---MAGSTAVVVLVKDN-KLYCANAGDSRAIACVNGQLEV 148
            |..|...||:||.....: :...|.   .:|:||.|.|::|. :|..|:.||||||.|..|:...
Human   157 ETLLTLAFLEIDKAFSSHARLSADATLLTSGTTATVALLRDGIELVVASVGDSRAILCRKGKPMK 221

  Fly   149 LSLDHKPNNEAESKRIIQGGGWVEFN-----RVNGNLALSRALGDYVFKHENKKPEDQIVTAFPD 208
            |::||.|..:.|.:||.:.||:|.:|     .|||.||::|::||...|...       |.|.| 
Human   222 LTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKTSG-------VIAEP- 278

  Fly   209 VETRKI----MDDWEFIVLACDGIWDVMSNAEVLEFCRTRIGMGMFPEEICEELMNHCLAPD--- 266
             ||::|    .|| .|:||..||| :.|.|:                :||| :.:|.|..|:   
Human   279 -ETKRIKLHHADD-SFLVLTTDGI-NFMVNS----------------QEIC-DFVNQCHDPNEAA 323

  Fly   267 -------CQMGGLGGDNMTVVLV 282
                   .|.|  ..||.|.|:|
Human   324 HAVTEQAIQYG--TEDNSTAVVV 344

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17746NP_647794.1 PP2Cc 22..284 CDD:238083 93/283 (33%)
PPM1KNP_689755.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 34..55
PP2Cc 95..346 CDD:238083 93/283 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0631
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG53745
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.820

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