Sequence 1: | NP_002259.1 | Gene: | KPNA4 / 3840 | HGNCID: | 6397 | Length: | 521 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001163572.1 | Gene: | Kap-alpha3 / 41158 | FlyBaseID: | FBgn0027338 | Length: | 514 | Species: | Drosophila melanogaster |
Alignment Length: | 516 | Identity: | 344/516 - (66%) |
---|---|---|---|
Similarity: | 409/516 - (79%) | Gaps: | 6/516 - (1%) |
- Green bases have known domain annotations that are detailed below.
Human 7 LDNQRLKNFKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPHEDICEDSDIDGDYRVQNT 71
Human 72 SLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAA 136
Human 137 WALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVV 201
Human 202 KPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWAL 266
Human 267 SYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHF 331
Human 332 PALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLT 396
Human 397 ISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAEDEAETIGNLIEECGGLEK 461
Human 462 IEQLQNHENEDIYKLAYEIIDQFFSSDDIDEDPSLVPEAIQGGTFGFNSSAN-VPTEGFQF 521 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
KPNA4 | NP_002259.1 | SRP1 | 11..513 | CDD:227396 | 341/501 (68%) |
Nuclear localization signal. /evidence=ECO:0000250 | 43..52 | 6/8 (75%) | |||
ARM 1, truncated | 66..106 | 18/39 (46%) | |||
armadillo repeat | 73..98 | CDD:293788 | 11/24 (46%) | ||
ARM 2 | 107..149 | 30/41 (73%) | |||
armadillo repeat | 109..142 | CDD:293788 | 22/32 (69%) | ||
NLS binding site (major). /evidence=ECO:0000250 | 137..229 | 72/91 (79%) | |||
armadillo repeat | 150..186 | CDD:293788 | 26/35 (74%) | ||
armadillo repeat | 192..227 | CDD:293788 | 27/34 (79%) | ||
ARM 4 | 195..233 | 30/37 (81%) | |||
ARM 5 | 234..278 | 34/43 (79%) | |||
armadillo repeat | 244..269 | CDD:293788 | 21/24 (88%) | ||
ARM 6 | 279..318 | 30/38 (79%) | |||
armadillo repeat | 279..311 | CDD:293788 | 24/31 (77%) | ||
NLS binding site (minor). /evidence=ECO:0000250 | 306..394 | 70/87 (80%) | |||
armadillo repeat | 319..355 | CDD:293788 | 30/35 (86%) | ||
ARM 8 | 361..400 | 28/38 (74%) | |||
armadillo repeat | 361..395 | CDD:293788 | 23/33 (70%) | ||
ARM 9 | 401..443 | 24/41 (59%) | |||
armadillo repeat | 404..438 | CDD:293788 | 20/33 (61%) | ||
ARM 10, atypical | 447..485 | 27/37 (73%) | |||
Kap-alpha3 | NP_001163572.1 | IBB | 7..88 | CDD:280005 | 40/82 (49%) |
SRP1 | 8..500 | CDD:227396 | 340/496 (69%) | ||
ARM | 104..224 | CDD:237987 | 90/119 (76%) | ||
armadillo repeat | 104..137 | CDD:293788 | 22/32 (69%) | ||
armadillo repeat | 145..181 | CDD:293788 | 26/35 (74%) | ||
armadillo repeat | 187..222 | CDD:293788 | 27/34 (79%) | ||
ARM | 236..350 | CDD:237987 | 94/113 (83%) | ||
armadillo repeat | 239..264 | CDD:293788 | 21/24 (88%) | ||
armadillo repeat | 272..308 | CDD:293788 | 28/35 (80%) | ||
armadillo repeat | 314..348 | CDD:293788 | 28/33 (85%) | ||
ARM | 315..433 | CDD:237987 | 85/117 (73%) | ||
armadillo repeat | 356..390 | CDD:293788 | 23/33 (70%) | ||
armadillo repeat | 399..433 | CDD:293788 | 20/33 (61%) | ||
Arm_3 | 442..485 | CDD:292804 | 29/44 (66%) |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 1 | 0.930 | - | - | C165143886 | |
Domainoid | 1 | 1.000 | 76 | 1.000 | Domainoid score | I8982 |
eggNOG | 1 | 0.900 | - | - | E1_COG5064 | |
Hieranoid | 1 | 1.000 | - | - | ||
Homologene | 1 | 1.000 | - | - | H20521 | |
Inparanoid | 1 | 1.050 | 676 | 1.000 | Inparanoid score | I726 |
Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S483 |
OMA | 1 | 1.010 | - | - | QHG54553 | |
OrthoDB | 1 | 1.010 | - | - | D1111872at2759 | |
OrthoFinder | 1 | 1.000 | - | - | FOG0000157 | |
OrthoInspector | 1 | 1.000 | - | - | otm40373 | |
orthoMCL | 1 | 0.900 | - | - | OOG6_104544 | |
Panther | 1 | 1.100 | - | - | LDO | PTHR23316 |
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R2158 |
SonicParanoid | 1 | 1.000 | - | - | X2405 | |
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 1 | 0.960 | - | - | ||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
17 | 16.750 |