DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Larp4B and LARP6b

DIOPT Version :9

Sequence 1:	NP_647793.1	Gene:	Larp4B / 38399	FlyBaseID:	FBgn0035424	Length:	1531	Species:	Drosophila melanogaster
Sequence 2:	NP_566004.1	Gene:	LARP6b / 819002	AraportID:	AT2G43970	Length:	545	Species:	Arabidopsis thaliana

Alignment Length:	770	Identity:	129/770 - (16%)
Similarity:	220/770 - (28%)	Gaps:	329/770 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 AASPAAAAAAHIPLITAAAAAAAAAGAPAVAP------------------------------PVA 79
            :::.:|::::...|:.:.:.:...||||...|                              |..
plant    27 SSTTSASSSSDPSLLRSLSLSRLNAGAPEFVPGRTTPPLPQPPRMIIPPPPPHGMLHMYHHQPPF 91

  Fly    80 VAPVATASAAQAAVVPAQQQQQAHPHQAQILAHTHVAHQQQQQQQQQTIQQHLHQQQQQQSPHPA 144
            ..||......|..:||.|..   |||..   .|.|..|.:.|.||...::.|...||:
plant    92 NTPVLGPVPIQPHLVPVQNH---HPHHR---FHQHHHHNRHQNQQYVPVRNHGEYQQR------- 143

  Fly   145 QHLTYGHQPALSQATAGGSGTISGGAVGPSGVVVEGQDTNEYAIMNGALGQTQDGTVVCYTTDAL 209
                                                          |.:|..|:..:|....|..
plant   144 ----------------------------------------------GGVGGEQEPDLVSKKNDRR 162

  Fly   210 NNTNLVALDPQPHQIVVPVQVPVQVPVPVQLPANGSADPQQGSHNAAGGEEPNIPLDKLKQMLAT 274
            :::...:.:.|                ..:..|:.|.|.:.|           :|.|.: |.:..
plant   163 DHSKRESKNDQ----------------VTETGASVSIDSKTG-----------LPEDSI-QKIVN 199

  Fly   275 QLEYYFSRENLANDTYLLSQM--DSDQYVPIYTVARFNLVRKLTNDINLITEVLRESPNVQVDDK 337
            |:|||||..|||...:|:..:  |.:.||||:.||.|..::.:.|:.:.:..||:.|..:.|.:.
plant   200 QVEYYFSDLNLATTDHLMRFICKDPEGYVPIHVVASFKKIKAVINNNSQLAAVLQNSAKLFVSED 264

  Fly   338 GLRVRPNRKRCIIILREISNNTPLDDVKALFSNESCPRPISCEFAANNSWYITFESDEDAQKAYK 402
            |.:|           |.||                   ||:                |.|
plant   265 GKKV-----------RRIS-------------------PIT----------------ESA----- 278

  Fly   403 YLREEVKEFQGKPIMARIKPK-----------SFINRIQAVPKNGYRLTSPPTANVFDPAGAGGA 456
                 ::|.|.:.|:|...|:           |.:..::.:      .|..|..|     |:|..
plant   279 -----IEELQSRIIVAENLPEDHCYQNLMKIFSTVGSVKNI------RTCQPQNN-----GSGAP 327

  Fly   457 TVSYAAAQQPRYLYTNGAAIAAPASVQYSNPVLIPIPQNQFYPGLVAGPWPPGTVAATTAHGQNF 521
            ..:.:||:....|::|    ...|.|:|.   ::.:.:........||.|..|.........|
plant   328 PAARSAAKSDGTLFSN----KVHAFVEYE---IVELAERAVTELSEAGNWRSGLKVRLMLKHQ-- 383

  Fly   522 YELGGNIFTTNPLPPQPVTAGFAQAPPPTSQAMVTPKP-QGGGRYNNNHRGNPNNVGGANSGPRA 585
                                              |.:| ||.||....|              .|
plant   384 ----------------------------------TKEPKQGQGRGRKGH--------------DA 400

  Fly   586 ESRSKPPRSTPSASHIQGGNIMPIQITAPIPGGMVSVVPTNIVQDPLQPAPLQQQPQQVIQQ--- 647
            :...:...:|.|                                   :..|:::|......:
plant   401 DVEHEEDDATTS-----------------------------------EQQPIEKQSDDCSGEWDT 430

  Fly   648 -IQQQPSSSAQQQQAATVQMNNTTR-----------HYPIKSNWKGGMQKNLDKSYSGGVATHHH 700
             :|:||....|..:.|..|.....|           |.  ..|.......|.:.:::|....|||
plant   431 HMQEQPIGEDQGNEKAAGQRKGRNRGRGKGRGRGQPHQ--NQNQNNNHSHNQNHNHNGRGNHHHH 493

  Fly   701 YTTQVQALPAHSHHLQAQQQLQGQTQQQHYQLASSSAASAPQVTYVTTAPAPQQP 755
            :..||...|:::.....:|...|:.|                      .|.|:.|
plant   494 HHHQVGTQPSNNPMNNMEQPGMGKQQ----------------------PPGPRMP 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Larp4B	NP_647793.1	LARP_4_5_like	269..343	CDD:153400	26/75 (35%)
Larp4B	NP_647793.1	RRM_LARP4_5_like	348..423	CDD:240876	11/74 (15%)
LARP6b	NP_566004.1	LARP_6	194..270	CDD:153402	26/87 (30%)
LARP6b	NP_566004.1	RRM_La_like_plant	285..380	CDD:240734	20/112 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910