Protein Alignment Larp4B and Larp7

DIOPT Version :10

• Sequence 1: NP_647793.1
• Gene: Larp4B / 38399
• FlyBaseID: FBgn0035424
• Length: 1531
• Species: Drosophila melanogaster
• Sequence 2: XP_038959070.1
• Gene: Larp7 / 686883
• RGDID: 1592474
• Length: 578
• Species: Rattus norvegicus
• Alignment Length: 650
• Identity: 132/650 - (20%)
• Similarity: 226/650 - (34%)
• Gaps: 217/650 - (33%)

  Fly   267 KLKQML---ATQLEYYFSRENLANDTYLLSQMDS--DQYVPIYTVARFNLVRKLTNDINLITEVL 326
            ::||:|   |.|::::|...||..|.:|..|::.  |.||.|..:..||.::|||.|..||...|
  Rat    31 RVKQVLADIAKQVDFWFGDANLHKDRFLREQIEKSRDGYVDISLLVSFNKMKKLTTDGKLIARAL 95

  Fly   327 RESPNVQVDDKGLRVRPNRKRCIIILREISNNTPLDDVKALFSNESCPRPISCEFAANNSW---- 387
            :.|..|::|.:|.|:|  ||:.:       ...|.|:.:.....|..|:.::      :||
  Rat    96 KSSSVVELDLEGTRIR--RKKPL-------GERPKDEEERTVYVELLPKNVT------HSWIERV 145

  Fly   388 -------------------------YITFESDEDAQKAYKYLREEVKEFQGKPIMARIKPKSFIN 427
                                     ::.||:.|.|.||.::|....:|...||   .|.||:..|
  Rat   146 FGKCGNVVYISIPHYKSTGDPKGFAFVEFETKEQAAKAIEFLNNPPEEAPRKP---GIFPKTVKN 207

  Fly   428 RIQAVP-------------KNGYRLTSPPTAN----VFDPAGAGGATVSYAAAQQPRYLYTNGAA 475
            :  .:|             |.| |:....:..    |.|.:.:|   || .|.::||.......|
  Rat   208 K--PIPSLRVAEEKKKKKKKKG-RIKKEESVQAKELVVDSSSSG---VS-KATKRPRTASEGSEA 265

  Fly   476 IAAPASVQYSNPVLIPIPQNQFYPGLVAGPWP---PGTVAATTAHGQNFYELGGNIFTTNPLPPQ 537
            ....|..|       |..:.:....:..|..|   .|....::|..::.            |||:
  Rat   266 ETPEAPKQ-------PAKKKKKRDKVETGGLPESKAGKRERSSAEDEDC------------LPPR 311

  Fly   538 PVTAGFAQAPPPTSQAMVTPKPQGGG----RYNNNHRG----------NPNNVGG--ANSGPRAE 586
            |.....||             ..|||    ..:..||.          .|.:..|  .:.|.|..
  Rat   312 PKLKKRAQ-------------KDGGGPAASEVSKEHRDLEFCSTEEEKEPGDRKGDSLSKGKRKH 363

  Fly   587 SRSKPPRSTPSASHIQGGNIMPIQITAPI-------------PGGMVSVVPTNIVQDPLQ----- 633
            .:....|      |..|..::|:::.:..             ...|.|:..| |.|..|:
  Rat   364 KKKHKER------HKMGEEVIPLRVLSKTEWMDLKKEYLALQKASMASLKKT-ISQIKLESEMET 421

  Fly   634 --PAPLQQQPQQVIQQIQQQPSSSAQQQQAATVQMNNTTRHYPIKSNWKGGMQ-KNLDKSYS--- 692
              .||    |....||...|...|||..|..|..:.......|:    .|..| |::..:.|
  Rat   422 ESKAP----PAGSGQQCSTQEKVSAQGPQFVTGVIVKILSEDPL----PGRKQVKDILATISEVV 478

  Fly   693 ------GGVATHHHYTT----------QVQALPAHSHHLQAQQQLQGQTQQQHYQLASSSAASAP 741
                  |....|..:.|          |.:....||.:|:.   |.|..:|:::|..
  Rat   479 YIDLLEGDTECHARFKTPEDAQAVMNAQTEIKKKHSWNLEI---LSGDHEQRYWQKI-------- 532

  Fly   742 QVTYVTTAPAPQQPGQHQHHLVVQQ---TQPQQQQQ-QQQVVLQQQQVQVQELQEAGDGVEHSSH 802
                                ||.:|   .||::::: .::::.:.:::::.:.|:|...:..|.:
  Rat   533 --------------------LVDRQAKLNQPREKKRGTEKLITKAEKIRLAKTQQASQHIRFSEY 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Larp4B	NP_647793.1	LARP_4_5_like	269..343	CDD:153400	29/78 (37%)
		RRM_LARP4_5_like	348..423	CDD:409864	17/103 (17%)
Larp7	XP_038959070.1	LARP_7	32..112	CDD:153401	30/81 (37%)
		RRM1_LARP7	127..206	CDD:409732	17/87 (20%)
		RRM2_LARP7	450..531	CDD:409958	15/87 (17%)