Protein Alignment Larp4B and Larp7

DIOPT Version :10

• Sequence 1: NP_647793.1
• Gene: Larp4B / 38399
• FlyBaseID: FBgn0035424
• Length: 1531
• Species: Drosophila melanogaster
• Sequence 2: NP_524795.2
• Gene: Larp7 / 44900
• FlyBaseID: FBgn0260771
• Length: 595
• Species: Drosophila melanogaster
• Alignment Length: 607
• Identity: 113/607 - (18%)
• Similarity: 200/607 - (32%)
• Gaps: 223/607 - (36%)

  Fly   219 PQPHQIVVPVQVPVQVPVPVQLPANGSADPQQGSHNAAGGEEPNIPLDKLKQMLAT----QLEYY 279
            |.|.....|.:...:.|.    |.:.|.|.:.|..             |.|:.|..    |:|:|
  Fly    23 PDPAAPTEPAEENSKEPA----PEDASPDKKDGGR-------------KRKRHLFNSIRGQMEFY 70

  Fly   280 FSRENLANDTYLLSQMDSDQYVPIYTVARFNLVRKLTNDINLITEVLRESPNVQVDDKGLRVR-- 342
            |...||:.|.:|...::.|.|||:.....||.::.||.|:..|.:.|..|..:::|:..|:|:
  Fly    71 FGDANLSKDRFLRRYVEQDPYVPLEIFLTFNKIKTLTQDVQQIAKALSNSQLLELDETELKVKRR 135

  Fly   343 ---PNRKRC---IIILREISNNTPLDDVKALFSNESCPRPISC----------EFAANNSWYITF 391
               |:::..   .:.:..:..|...|.:|.:||.......:|.          |||     :|.|
  Fly   136 TKLPDQRDVNDKTLYVEALPANATHDWLKEVFSRYGPVAYVSLPHYPGTKKIKEFA-----FIEF 195

  Fly   392 ESDEDAQKAYKYLRE---------------EVKEFQGKPIMAR--IKPKSFINRIQAVPKNGYR- 438
            |.....:||.|...:               .|:.||.:..:.:  .:|:|...::: :||...:
  Fly   196 EKSGSLEKAVKAFAQIQGVLSVETDPSDLASVRSFQQQQQIQQKAEQPQSEAEQVE-LPKRNLKR 259

  Fly   439 --------------------------LTSPPTANVFDPAGAGGATVSYAAAQQPRYLYTNGAAIA 477
                                      .|:..||:..|..|     .:.|:.|:.:...|:|...|
  Fly   260 EATDKDREEIHEVKRVKLEEGQPSETSTAGETASETDAEG-----TAEASEQEDKTEATDGDEAA 319

  Fly   478 ------------------APASVQYSNPVLIP------------------------------IPQ 494
                              .|::::..   ::|                              .||
  Fly   320 KKRRRKRKKKAIVDKPNIEPSALELK---VLPKTSWSSMRNKYLNLQRRIVSEAKSKLWRENHPQ 381

  Fly   495 NQFYPGLVAGPWPPGTVAATTAHGQNFYELGGNIFTTNPLPPQP----------VTAGFAQAPPP 549
            ||.:|                 |.|.         |::|..|:|          .|.|  :.|..
  Fly   382 NQQHP-----------------HHQQ---------TSHPNHPKPSQLPEAVKEEETGG--EVPSD 418

  Fly   550 TSQAMVTPKPQGGGRYNNNHRGNPN--NVGGANSGPRAESRSKPP--RSTPSASHIQGGNIMPIQ 610
            ..:..|...|....|....|:.|.|  ..||..|     ::|:.|  ..||...: :.|.|:...
  Fly   419 GGEGAVEAAPVPAKRRKAVHKMNMNFYGAGGVES-----TKSEEPSQERTPLFKY-EPGLIVECS 477

  Fly   611 ITAPIPGGMVSVVPTNIVQDPLQPAPLQQQPQQVIQQIQQ----------QPSSSAQQQQAATVQ 665
            :..|.         ||:.:   ..|.::|.|......|::          .|:::.:..:    |
  Fly   478 LLKPC---------TNVKE---FKAEMRQYPDIKYVDIKEGDQVALLRLGTPAAAEELLR----Q 526

  Fly   666 MNNTTRHYPIKSNWKGGMQKNL 687
            :|.:.|...:.|    |.|:.|
  Fly   527 VNCSERQLKVLS----GQQETL 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Larp4B	NP_647793.1	LARP_4_5_like	269..343	CDD:153400	25/82 (30%)
		RRM_LARP4_5_like	348..423	CDD:409864	18/104 (17%)
Larp7	NP_524795.2	LA	57..135	CDD:128955	24/77 (31%)
		RRM1_LARP7	148..220	CDD:409732	15/76 (20%)
		RRM2_LARP7	471..548	CDD:409958	17/94 (18%)