Protein Alignment Larp4B and La

DIOPT Version :10

• Sequence 1: NP_647793.1
• Gene: Larp4B / 38399
• FlyBaseID: FBgn0035424
• Length: 1531
• Species: Drosophila melanogaster
• Sequence 2: NP_477014.1
• Gene: La / 35305
• FlyBaseID: FBgn0011638
• Length: 390
• Species: Drosophila melanogaster
• Alignment Length: 290
• Identity: 70/290 - (24%)
• Similarity: 105/290 - (36%)
• Gaps: 99/290 - (34%)

  Fly   226 VPVQVPVQVPVPVQL--PANGSA--DPQQGSHNAAGGEEPNIPLDKLKQMLATQLEYYFSRENLA 286
            |..|..|..|...|:  ..||.|  ||...:..||||      ..|.::.:..|:||||...||.
  Fly    10 VEAQEEVAQPAEAQVLEAKNGDAKKDPAPAAEEAAGG------FTKQERAIIRQVEYYFGDANLN 68

  Fly   287 NDTYLLSQM--DSDQYVPIYTVARFNLVRKLTNDINLITEVLRESP----NVQVDDKGLRVRPNR 345
            .|.:|..|:  :.|.:||:..:..|..:..|:.|::.|...|.:|.    .:..|...||..|.|
  Fly    69 RDKFLREQIGKNEDGWVPLSVLVTFKRLASLSTDLSEIVAALNKSEEGLVEISEDKLSLRRHPER 133

  Fly   346 --------KRCIIILREISNNT------PLD-DVKALFSNESCPRPISCEFAAN----------- 384
                    :|     :||...|      ||| .:..|.           :||||
  Fly   134 PIPEHNEERR-----KEIQERTAYAKGFPLDSQISELL-----------DFAANYDKVVNLTMRK 182

  Fly   385 ------------NSWYITFESDEDAQK-------AYK-----------YLREEVKEF-------- 411
                        .|.::|||:.:.|:.       .||           ||:|:.:|:
  Fly   183 HYDKPTKSYKFKGSIFLTFETKDQAKAFLEQEKIVYKERELLRKWQVDYLKEKQEEYAQKNEKRK 247

  Fly   412 ---QGKPIMARIKPKSFINRIQAVPKNGYR 438
               :.||..|...||:.|...:..|:...|
  Fly   248 NKKEAKPEPAFELPKNAIVVFEGAPETSSR 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Larp4B	NP_647793.1	LARP_4_5_like	269..343	CDD:153400	22/79 (28%)
		RRM_LARP4_5_like	348..423	CDD:409864	25/133 (19%)
La	NP_477014.1	LARP_3	47..129	CDD:153397	22/81 (27%)
		RRM1_La	150..226	CDD:409733	16/86 (19%)
		RRM2_La	263..338	CDD:409957	3/15 (20%)