Protein Alignment Larp4B and Larp7

DIOPT Version :10

• Sequence 1: NP_647793.1
• Gene: Larp4B / 38399
• FlyBaseID: FBgn0035424
• Length: 1531
• Species: Drosophila melanogaster
• Sequence 2: NP_613059.2
• Gene: Larp7 / 28036
• MGIID: 107634
• Length: 570
• Species: Mus musculus
• Alignment Length: 654
• Identity: 124/654 - (18%)
• Similarity: 216/654 - (33%)
• Gaps: 226/654 - (34%)

  Fly   267 KLKQML---ATQLEYYFSRENLANDTYLLSQMDS--DQYVPIYTVARFNLVRKLTNDINLITEVL 326
            ::||:|   |.|::::|...||..|.:|..|::.  |.||.|..:..||.::|||.|..||...|
Mouse    24 RVKQVLADIAKQVDFWFGDANLHKDKFLREQIEKSRDGYVDISLLVSFNKMKKLTTDGKLIARAL 88

  Fly   327 RESPNVQVDDKGLRVRPNRKRCIIILREISNNTPLDDVKALFSNESCPRPISCEFAANNSW---- 387
            :.|..|::|.:|.|:|  ||:.:       ...|.|:.:.....|..|:.::      :||
Mouse    89 KSSSVVELDLEGTRIR--RKKPL-------GERPKDEEERTVYVELLPKNVT------HSWIERV 138

  Fly   388 -------------------------YITFESDEDAQKAYKYLREEVKEFQGKPIMARIKPKSFIN 427
                                     ::.||:.|.|.||.::|....:|...||   .|.||:..|
Mouse   139 FGKCGNVVYISIPHYKSTGDPKGFAFVEFETKEQAAKAIEFLNNPPEEAPRKP---GIFPKTVKN 200

  Fly   428 RIQAVPKNGYRLTSPPTANVFDPAGAGGATVSYAAAQQPRYLYTNGAAIAAPASVQYSNPVLIPI 492
            :  .:|                         |...|::.:........|....|||.....:
Mouse   201 K--PIP-------------------------SLRVAEEKKKKKKKKGRIKKEESVQAKESAV--- 235

  Fly   493 PQNQFYPGLVAGPWPPGTVAATTAHGQNFYELGGNIFTTNPLPPQP-----------------VT 540
              :....|:......|.|.:.            |:...|...|.||                 ..
Mouse   236 --DSSSSGVCKATKRPRTASE------------GSEAETPEAPKQPAKKKKKRDKVEASSLPEAR 286

  Fly   541 AGFAQAPPPTSQAMVTPKPQGGGRYNNNHRGNPNNVGGANSGPRAESR----------SKPPRST 595
            ||..:......:..:.|:|:.      ..|...:.||.|.|....|||          .:..|..
Mouse   287 AGKRERCSAEDEDCLPPRPKA------KKRAQKDGVGQAASEVSKESRDLEFCSTEEEKETDRKG 345

  Fly   596 PSAS-------------HIQGGNIMPIQITAPI-------------PGGMVSVVPTNIVQDPLQ- 633
            .|.|             |..|..::|:::.:..             ...|.|:..| |.|..|:
Mouse   346 DSLSKVKRKHKKKHKERHKMGEEVIPLRVLSKTEWMDLKKEYLALQKASMASLKKT-ISQIKLES 409

  Fly   634 ------PAPLQQQPQQVIQQIQQQPSSSAQQQQAATVQMNNTTRHYPIKSNWKGGMQ-KNLDKSY 691
                  .||.....    |:...|...|||..|..|..:.......|:    .|..| |::..:.
Mouse   410 EMETDCKAPTAGSG----QECSTQEKVSAQGPQFVTGVIVKIVSGEPL----PGRKQVKDILATI 466

  Fly   692 S---------GGVATHHHYTT----------QVQALPAHSHHLQAQQQLQGQTQQQHYQLASSSA 737
            |         |....|..:.|          |.:....||.:|:.   |.|..:|:::|..
Mouse   467 SEVVYIDLLEGDTECHARFKTPEDAQAVMNAQTEIRKKHSWNLEV---LSGDHEQRYWQKI---- 524

  Fly   738 ASAPQVTYVTTAPAPQQPGQHQHHLVVQQ---TQPQQQQQ-QQQVVLQQQQVQVQELQEAGDGVE 798
                                    ||.:|   .||::::: .::::.:.:::::.:.|:|...:.
Mouse   525 ------------------------LVDRQAKLNQPREKKRGTEKLITKAEKIRLAKTQQASQHIR 565

  Fly   799 HSSH 802
            .|.:
Mouse   566 FSEY 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Larp4B	NP_647793.1	LARP_4_5_like	269..343	CDD:153400	29/78 (37%)
		RRM_LARP4_5_like	348..423	CDD:409864	17/103 (17%)
Larp7	NP_613059.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24		124/654 (19%)
		LARP_7	25..105	CDD:153401	30/81 (37%)
		RRM1_LARP7	120..199	CDD:409732	17/87 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	180..364		38/236 (16%)
		RRM2_LARP7	442..523	CDD:409958	15/87 (17%)