Protein Alignment Larp4B and Larp4b

DIOPT Version :10

• Sequence 1: NP_647793.1
• Gene: Larp4B / 38399
• FlyBaseID: FBgn0035424
• Length: 1531
• Species: Drosophila melanogaster
• Sequence 2: XP_011242555.1
• Gene: Larp4b / 217980
• MGIID: 106330
• Length: 1723
• Species: Mus musculus
• Alignment Length: 966
• Identity: 253/966 - (26%)
• Similarity: 376/966 - (38%)
• Gaps: 281/966 - (29%)

  Fly    38 FGATTQIAASPAAAAAAHIPLITAAAAAAAAAGAPAVAPPVAVAPVATASAAQAAVVPAQQQQQA 102
            |..|....:|...::...:..|.....||:...||...|       |..:.....|||:..|.
Mouse   854 FKKTALHDSSEVCSSLIDVKSIRVDMPAASPGNAPLAIP-------AIPADNTGCVVPSADQD-- 909

  Fly   103 HPHQAQILAHTHVAHQQQQQQQQQTIQQHLHQQQQQQSPHPAQHLTYGHQPAL-SQA---TAGGS 163
                       |:|...:...:..: :...|:..::...|.....:|.....| |||   .|||.
Mouse   910 -----------HIASPTEGVSENPS-EMDWHRIPEEFYAHFLNEFSYYPVGGLASQALSGLAGGC 962

  Fly   164 GTISGGAV----GPSGVVVEGQDTNE------YAIMNGA---------LGQTQDGTV-------- 201
            |....|.:    ....:..:.|..||      ..:.|.:         |..|:||.:
Mouse   963 GRYQVGYLWANTATENMTEDAQFFNEDLHSKPQYLENTSFSLEQTPFQLPVTEDGVIWGWPSRGG 1027

  Fly   202 -VCYTT--DALN------NTNLVALDPQPHQIVV----------PVQVPVQVPVPVQLPANGSAD 247
             :..||  ..||      .|:::.|:.....:.|          |.....||   :.|.|||..|
Mouse  1028 QLVPTTKVSELNPNAKVWGTHMLHLEASSAAVGVNAAWEEAPGHPTDCDQQV---LGLDANGDGD 1089

  Fly   248 PQQGS-----------------------------HNAAGGEE--PNIPLDKLKQMLATQLEYYFS 281
            ..:.:                             :|..||.|  |....|. :::|...||:..|
Mouse  1090 KSRENAALPDAQEAEQTDMSTLALDHSEYEPLPENNDTGGNESQPESQEDP-REVLKKTLEFCLS 1153

  Fly   282 RENLANDTYLLSQMDSDQYVPIYTVARFNLVRKLTNDINLITEVLRESPNVQVDDKGLRVRPNRK 346
            |||||:|.||:|||||||||||.|||..:.::||:.|::||.||||..|.||||:||.:||||:.
Mouse  1154 RENLASDMYLISQMDSDQYVPITTVANLDHIKKLSTDVDLIVEVLRSLPLVQVDEKGEKVRPNQN 1218

  Fly   347 RCIIILREISNNTPLDDVKALFSNESCPRPISCEFAANNSWYITFESDEDAQKAYKYLREEVKEF 411
            |||:||||||.:||:::|:|||..::.|:.|:||||.|::|:||||::.|||:|||||||||:.|
Mouse  1219 RCIVILREISESTPVEEVEALFKGDNLPKFINCEFAYNDNWFITFETEADAQQAYKYLREEVRTF 1283

  Fly   412 QGKPIMARIKPKSF-INRIQAVPKNGYRLTSPPTANVFDPAGAGGATVSYAAAQQPRYLYTNGAA 475
            |||||.||||.|:. ||..  :||||:|   |...|::               .|.||
Mouse  1284 QGKPIKARIKAKAIAINTF--LPKNGFR---PLDMNLY---------------TQQRY------- 1321

  Fly   476 IAAPASVQYSNPVLIPIPQNQFYPGLVAGPWPPGTVAATTAHGQNFYELGGNIFTTNPLPPQPVT 540
                |:..|..||.  .||.||                      ..|.|         :.||..:
Mouse  1322 ----ATSFYLPPVY--SPQQQF----------------------PLYSL---------ITPQTWS 1349

  Fly   541 AGFAQAPPPTSQAMVTPKPQGGGRYNNNHRGNPNNVGGANS-------GPRAESRSKPPRS-TPS 597
            ...:...||    :|||.|..|            .:.|..|       .|....|..|||| .||
Mouse  1350 TTHSYLDPP----LVTPFPSTG------------FINGFTSPTFKPATSPLTSLRQYPPRSRNPS 1398

  Fly   598 ASHIQGGNIMPIQITAPIPGGMVSVVPTNIVQDPL---QPAPLQQQPQQVIQQIQQQPSSSAQQQ 659
            .||::..    |..|...||.:.|....|...|.|   ..:|..:|..|...:| |.||:.|:::
Mouse  1399 KSHLRHA----IPSTERGPGLLESPSIFNFTADRLINGVRSPQTRQAGQTRTRI-QNPSAYAKRE 1458

  Fly   660 QAATVQMNNTTRHYPIKSNWKGGMQKNLDKSYSGGVATHHHYT-TQVQA---------------- 707
                   ..|.|..|.......|:.:....|:.........:| :|.|:
Mouse  1459 -------IGTGRVEPSSLESSPGLGRGRKNSFGYRKKREEKFTSSQTQSPTPPKPPSPSFELGLS 1516

  Fly   708 ----LPAHSHHLQAQQQLQ--------GQTQQQHYQLASSS---------AASAPQVTYVTTA-- 749
                ||..:.:|:.:...:        |.:::::....:|:         ..|.|....|:.|
Mouse  1517 NFPPLPGAAGNLKTEDLFENRLSSLIIGSSKERNLSTDASTNTVPVVGPREPSVPAPCAVSAAFE 1581

  Fly   750 --PAPQQPGQHQHHLVVQQTQPQQQQQQQQV--------VLQQQQVQVQELQEAGDGVEHSSHAM 804
              |:|.       ||.......::|::.|.|        ....:.|||.     |...|....:.
Mouse  1582 RSPSPV-------HLPEDPKVAEKQRETQSVDRLPSTPTTTACKSVQVN-----GAATELRKPSY 1634

  Fly   805 QQVNRSSNMSASSSSSLATSMSKEPL--------QWQNRPRRRRRDEEGGINYSPG 852
            .::.:.::...||||.|.....::|.        :..:.|..|.| |...:..:||
Mouse  1635 AEICQRTSKDPSSSSPLQPPKEQKPSTVACGKEEKQLSEPVERHR-EPPALKSTPG 1689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Larp4B	NP_647793.1	LARP_4_5_like	269..343	CDD:153400	43/73 (59%)
		RRM_LARP4_5_like	348..423	CDD:409864	48/74 (65%)
Larp4b	XP_011242555.1	LARP_5	1141..1215	CDD:153405	43/73 (59%)
		RRM_LARP5	1220..1296	CDD:410105	48/75 (64%)