DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32271 and PRSS1

DIOPT Version :9

Sequence 1:	NP_728833.1	Gene:	CG32271 / 38392	FlyBaseID:	FBgn0052271	Length:	248	Species:	Drosophila melanogaster
Sequence 2:	XP_011514713.1	Gene:	PRSS1 / 5644	HGNCID:	9475	Length:	472	Species:	Homo sapiens

Alignment Length:	237	Identity:	87/237 - (36%)
Similarity:	126/237 - (53%)	Gaps:	16/237 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LVLHLIPLCWAASNEANSRIVGGVPVDIASVPYLVNLRIGGNFMCGGSLVTPQHVVTAAHCVKG- 69
            |:|..:....||..:.:.:||||...:..||||.|:|..|.:| |||||:..|.||:|.||.|.
Human   230 LILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHF-CGGSLINEQWVVSAGHCYKSR 293

  Fly    70 ----IGASRILVVAGVTRLTETGVRSGVDKVYTPKAYNTRTLTSDVAVLKLKA-PISGPKVSTIE 129
                :|...|.|:.|..:.....      |:.....|:.:||.:|:.::||.: .:...:||||.
Human   294 IQVRLGEHNIEVLEGNEQFINAA------KIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTIS 352

  Fly   130 LCNTSFKAGDLIKVSGWGQITERNKAVSMQVRSVDVALIPRKACMSQYKLRGTITNTMFCAS-VP 193
            |.......|....:||||...........:::.:|..::.:..|.:.|.  |.||:.|||.. :.
Human   353 LPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYP--GKITSNMFCVGFLE 415

  Fly   194 GVKDACEGDSGGPAVYQGQLCGIVSWGVGCARKSSPGVYTNV 235
            |.||:|:||||||.|..|||.|:||||.|||:|:.|||||.|
Human   416 GGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKV 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32271	NP_728833.1	Tryp_SPc	24..242	CDD:214473	83/219 (38%)
CG32271	NP_728833.1	Tryp_SPc	25..244	CDD:238113	83/218 (38%)
PRSS1	XP_011514713.1	Ig	19..119	CDD:299845
		IG_like	29..113	CDD:214653
		Tryp_SPc	248..464	CDD:214473	83/219 (38%)
		Tryp_SPc	249..467	CDD:238113	83/218 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBP0
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820