Protein Alignment CG32271 and PLAT

DIOPT Version :10

• Sequence 1: NP_728833.1
• Gene: CG32271 / 38392
• FlyBaseID: FBgn0052271
• Length: 248
• Species: Drosophila melanogaster
• Sequence 2: NP_000921.1
• Gene: PLAT / 5327
• HGNCID: 9051
• Length: 562
• Species: Homo sapiens
• Alignment Length: 264
• Identity: 81/264 - (30%)
• Similarity: 124/264 - (46%)
• Gaps: 32/264 - (12%)

  Fly    11 IPLCWAAS----NEANSRIVGGVPVDIASVPYLVNL------RIGGNFMCGGSLVTPQHVVTAAH 65
            :|.|....    ::...||.||:..||||.|:...:      ..|..|:|||.|::...:::|||
Human   293 VPSCSTCGLRQYSQPQFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAH 357

  Fly    66 CV-KGIGASRILVVAGVTRLTETG---VRSGVDKVYTPKAYNTRTLTSDVAVLKLKAPIS----- 121
            |. :......:.|:.|.|.....|   .:..|:|....|.::..|..:|:|:|:||:..|
Human   358 CFQERFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQE 422

  Fly   122 GPKVSTIELCNTSFKAGDL--IKVSGWGQITERNKAVSMQVRSVDVALIPRKACMSQYKLRGTIT 184
            ...|.|:.|.....:..|.  .::||:|:....:...|.:::...|.|.|...|.||:.|..|:|
Human   423 SSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVT 487

  Fly   185 NTMFCAS-------VPGVKDACEGDSGGPAVYQGQ----LCGIVSWGVGCARKSSPGVYTNVKTV 238
            :.|.||.       ...:.|||:||||||.|....    |.||:|||:||.:|..|||||.|...
Human   488 DNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDVPGVYTKVTNY 552

  Fly   239 RSFI 242
            ..:|
Human   553 LDWI 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32271	NP_728833.1	Tryp_SPc	24..242	CDD:214473	78/245 (32%)
PLAT	NP_000921.1	FN1	41..83	CDD:214494
		Important for binding to annexin A2	42..52
		EGF	86..117	CDD:394967
		KR	125..209	CDD:238056
		Kringle	215..296	CDD:395005	1/2 (50%)
		Tryp_SPc	313..559	CDD:238113	77/244 (32%)