DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32271 and PRSS36

DIOPT Version :9

Sequence 1:	NP_728833.1	Gene:	CG32271 / 38392	FlyBaseID:	FBgn0052271	Length:	248	Species:	Drosophila melanogaster
Sequence 2:	NP_775773.2	Gene:	PRSS36 / 146547	HGNCID:	26906	Length:	855	Species:	Homo sapiens

Alignment Length:	253	Identity:	86/253 - (33%)
Similarity:	129/253 - (50%)	Gaps:	27/253 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 EANSRIVGGVPVDIASVPYLVNLRIGGNFMCGGSLVTPQHVVTAAHCVKGIG----ASRILVVAG 80
            |.::|||||......:.|:.|:|..||..:|||||:.|..|::||||....|    |:...|:.|
Human    42 EPSARIVGGSNAQPGTWPWQVSLHHGGGHICGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSVLLG 106

  Fly    81 VTRLTETGVRSG-----VDKVYTPKAYNTRTLTSDVAVLKLKAPIS-GPKVSTIELCNTS--FKA 137
            |.  ::.|...|     |..:..|..|:...|.:|:|:|:|.:|.| ||.|..:.|...|  |..
Human   107 VH--SQDGPLDGAHTRAVAAIVVPANYSQVELGADLALLRLASPASLGPAVWPVCLPRASHRFVH 169

  Fly   138 GDLIKVSGWGQITERNK-AVSMQVRSVDVALIPRKACMSQYKLRGTITNT------MFCASVP-G 194
            |.....:|||.:.|.:. .:...::.|::.|:....|...|...|....|      |.||..| |
Human   170 GTACWATGWGDVQEADPLPLPWVLQEVELRLLGEATCQCLYSQPGPFNLTLQILPGMLCAGYPEG 234

  Fly   195 VKDACEGDSGGPAVYQ--GQ--LCGIVSWGVGCARKSSPGVYTNVKTVRSFI-DKALG 247
            .:|.|:||||||.|.:  |:  ..||.|:|.||.|::.|||:|.|.|..::| ::.:|
Human   235 RRDTCQGDSGGPLVCEEGGRWFQAGITSFGFGCGRRNRPGVFTAVATYEAWIREQVMG 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32271	NP_728833.1	Tryp_SPc	24..242	CDD:214473	83/241 (34%)
CG32271	NP_728833.1	Tryp_SPc	25..244	CDD:238113	83/243 (34%)
PRSS36	NP_775773.2	Tryp_SPc	46..286	CDD:214473	83/241 (34%)
		Tryp_SPc	47..289	CDD:238113	83/243 (34%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	292..316		1/1 (100%)
		Tryp_SPc	330..538	CDD:304450
		Tryp_SPc	601..783	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100