Protein Alignment Hsp83 and Trap1

DIOPT Version :9

• Sequence 1: NP_001261362.1
• Gene: Hsp83 / 38389
• FlyBaseID: FBgn0001233
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_080784.1
• Gene: Trap1 / 68015
• MGIID: 1915265
• Length: 706
• Species: Mus musculus
• Alignment Length: 691
• Identity: 216/691 - (31%)
• Similarity: 368/691 - (53%)
• Gaps: 114/691 - (16%)

  Fly    10 FQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELYIKLIPNKTA 74
            ||||..:|:.::..:.||.||:|:|||||||||||:|:|::.:.:...|   .|:.|.|..:...
Mouse    92 FQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVCEGQVL---PEMEIHLQTDAKK 153

  Fly    75 GTLTIIDTGIGMTKSDLVNNLGTIAKSGTKAFMEALQAGADIS--MIGQFGVGFYSAYLVADKVT 137
            ||:||.|||||||:.:||:||||||:||:|||:||||..|:.|  :|||||||||||::|||||.
Mouse   154 GTITIQDTGIGMTQEELVSNLGTIARSGSKAFLEALQNQAETSSKIIGQFGVGFYSAFMVADKVE 218

  Fly   138 VTSKNNDDEQ--YVWESSAGGSFTV-RADNSEPLGRGTKIVLYIKEDQTDYLEESKIKEIVNKHS 199
            |.|::...|.  |.|.|...|.|.: .|....|   ||||::::|.|..|:..||:::::|.|:|
Mouse   219 VYSRSAAPESPGYQWLSDGSGVFEIAEASGVRP---GTKIIIHLKSDCKDFASESRVQDVVTKYS 280

  Fly   200 QFIGYPIKLLVEKEREKEVSDDEADDEKKEGDEKKEMETDEPKIEDVGEDEDADKKDKDAKKKKT 264
            .|:.:|:
Mouse   281 NFVSFPL---------------------------------------------------------- 287

  Fly   265 IKEKYTEDEELNKTKPIWTRNPDDISQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIP 329
                |...:.:|..:.||..:|.|||:.::.|||:.:...::......|:..:..|..|::.::|
Mouse   288 ----YLNGKRINTLQAIWMMDPKDISEFQHEEFYRYIAQAYDKPRFTLHYKTDAPLNIRSIFYVP 348

  Fly   330 RRTP--FDLFENQKKRNNIKLYVRRVFIMDNCEDLIPEYLNFMKGVVDSEDLPLNISREMLQQNK 392
            ...|  ||:  :::..:::.||.|:|.|.....|::|::|.|::|||||||:|||:|||:||::.
Mouse   349 EMKPSMFDV--SRELGSSVALYSRKVLIQTKAADILPKWLRFIRGVVDSEDIPLNLSRELLQESA 411

  Fly   393 VLKVIRKNLVKKTME-LIEELTEDKENYKKFYDQFSKNLKLGVHEDSNNRAK--LADFLRFHTSA 454
            :::.:|..|.::.:: .|::..:|.|.|.||::.:...::.|:...:....|  :|..||:.:||
Mouse   412 LIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTTAEQDIKEDIAKLLRYESSA 476

  Fly   455 -SGDDFCSLADYVSRMKDNQKHVYFITGESKDQVSNSAFVERVKARGFEVVYMTEPIDEYVIQHL 518
             ......||.||.|||:...:::|::...::....:|.:.|.:|.:..||::..|..||..:.||
Mouse   477 LPAGQLTSLPDYASRMQAGTRNIYYLCAPNRHLAEHSPYYEAMKQKHTEVLFCYEQFDELTLLHL 541

  Fly   519 KEYKGKQLVSVT--------KEGLELPEDESEKKKREEDKAKFESLCKLMKSILDNKVEKVVVSN 575
            :|:..|:|:||.        ||  |..||.|...:|..:| :.|.|...|::.|.::|..|.|:.
Mouse   542 REFDKKKLISVETDIVVDHYKE--EKFEDTSPADERLSEK-ETEDLMAWMRNALGSRVTNVKVTF 603

  Fly   576 RLVDSPCCIVTSQFGWSANMERIM--------KAQALRDTATMGYMAGKKQLEINPDHPIVETLR 632
            ||...|..:...:.|.:.:..|:.        :||.|:.|           |||||.|.:::.|.
Mouse   604 RLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPT-----------LEINPRHTLIKKLC 657

  Fly   633 QKADADKNDKAVKDLVILLFETSLLSSGFSLDSPQVHASRI 673
            |..:::  .:..:.||..::|.:::::|. :|.|:....|:
Mouse   658 QLRESE--PELAQLLVDQIYENAMIAAGL-VDDPRAMVGRL 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp83	NP_001261362.1	PTZ00272	6..717	CDD:240341	216/691 (31%)
		HATPase_c	28..179	CDD:214643	80/155 (52%)
		HSP90	184..706	CDD:278607	127/512 (25%)
Trap1	NP_080784.1	PRK05218	89..704	CDD:235366	216/691 (31%)
		HATPase_c	114..222	CDD:238030	65/110 (59%)
		HSP90	265..699	CDD:278607	127/512 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0326
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D924636at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820