DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14964 and Egflam

DIOPT Version :9

Sequence 1:	NP_647779.2	Gene:	CG14964 / 38384	FlyBaseID:	FBgn0035410	Length:	1443	Species:	Drosophila melanogaster
Sequence 2:	XP_006232075.1	Gene:	Egflam / 365691	RGDID:	1306592	Length:	1013	Species:	Rattus norvegicus

Alignment Length:	293	Identity:	67/293 - (22%)
Similarity:	107/293 - (36%)	Gaps:	90/293 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   272 EVIA---PGGRFEVSNTEKNSLLKIDNVLREDRGEYMVKAWNRLGEDSTSFLVTVTA-------R 326
            |||.   ||..:.||                      :.|:::.|:...||...||.       .
  Rat    99 EVIGDLKPGTEYRVS----------------------IAAYSQTGKGRLSFPRHVTTLSQDSCLP 141

  Fly   327 PNPPGTPKLNMSFGKSATLSWTAPLDDGGCKIGNYIVEYFR----VGWNVWLKAATTRALSTTLH 387
            |..|..|.:.:.......|||....::|...|.:|.||:.|    ..|.:..:  ..:..|..:.
  Rat   142 PEAPHQPHVLVVSDSEVALSWRPGENEGSAPIQSYSVEFIRPDFDKSWTIIQE--RLQMDSMVIK 204

  Fly   388 DLIEGSEYKFRVKAENPYGL---SEPSGESELL-------------FIPDPKRGIT--------- 427
            .|...:.|:|.|:|.|.||.   |:||.....|             :|.|  .|::
  Rat   205 GLDPDTNYQFAVRAMNAYGFSLRSQPSNTIRTLGPGEAGSGRYGPGYITD--TGVSEDDDASEDE 267

  Fly   428 ----------KPKSATRIAGDEKDKPKTGAGGMQVPPRRKTLSPPRPQADASTGMSPKQSPSAKR 482
                      ||..||:: |::|.| ||.....::..|   |:.|...:...|.::...:| |:|
  Rat   268 LDLDVSFEEVKPLPATKV-GNKKSK-KTSVSNSEMDSR---LAQPTSASLPETTVAVPPTP-AQR 326

  Fly   483 KPK------PQLID---NEQLTHEMSYGTSDHA 506
            |.|      .:|.|   :|.|....|:..:|:|
  Rat   327 KGKNSVAVMSRLFDMSCDETLCSADSFCVNDYA 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14964	NP_647779.2	FN3	29..127	CDD:238020
		I-set	138..227	CDD:254352
		Ig	155..224	CDD:143165
		IG_like	243..323	CDD:214653	11/53 (21%)
		Ig	250..323	CDD:299845	11/53 (21%)
		FN3	327..411	CDD:238020	23/90 (26%)
Egflam	XP_006232075.1	FN3	36..133	CDD:238020	12/55 (22%)
		FN3	142..236	CDD:238020	25/95 (26%)
		LamG	387..537	CDD:238058
		EGF_CA	556..598	CDD:238011
		Laminin_G_2	637..763	CDD:280389
		EGF_CA	786..816	CDD:238011
		Laminin_G_2	864..989	CDD:280389
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0613
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900