DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14964 and AgaP_AGAP006746

DIOPT Version :9

Sequence 1:	NP_647779.2	Gene:	CG14964 / 38384	FlyBaseID:	FBgn0035410	Length:	1443	Species:	Drosophila melanogaster
Sequence 2:	XP_308996.3	Gene:	AgaP_AGAP006746 / 1270312	VectorBaseID:	AGAP006746	Length:	344	Species:	Anopheles gambiae

Alignment Length:	152	Identity:	35/152 - (23%)
Similarity:	57/152 - (37%)	Gaps:	35/152 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   291 LKIDNVLREDRGEYMVKAWNRLGEDSTSFLVTVTARPNPPGTPKLNMSFGKSATLSWTAPLDDGG 355
            :|.:|:|      .:.|..||:......|     ||...|| .||.:.||   |..:.||
Mosquito   162 MKPENIL------CLTKTGNRIKIIDFGF-----ARRYDPG-KKLQVMFG---TAEFAAP----- 206

  Fly   356 CKIGNYIVEYFRVGWNVWLKAATTRALSTTLHDLIEGSE-----------YKFRVKAENPYGLSE 409
             ::.|:...||..  ::|........|.:.|...:.|.:           |.|..|:.:....|.
Mosquito   207 -EVLNFDEIYFYT--DMWSLGVICYVLLSGLSPFVGGDDQATMTNVLQGAYTFDYKSFDAVSDSA 268

  Fly   410 PSGESELLFIPDPKRGITKPKS 431
            .....:|| :.|.:|.:|..|:
Mosquito   269 KDFVRKLL-VRDGERRLTARKA 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14964	NP_647779.2	FN3	29..127	CDD:238020
		I-set	138..227	CDD:254352
		Ig	155..224	CDD:143165
		IG_like	243..323	CDD:214653	7/31 (23%)
		Ig	250..323	CDD:299845	7/31 (23%)
		FN3	327..411	CDD:238020	20/94 (21%)
AgaP_AGAP006746	XP_308996.3	S_TKc	40..295	CDD:214567	35/152 (23%)
AgaP_AGAP006746	XP_308996.3	PKc_like	46..295	CDD:304357	35/152 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0613
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900