DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Asciz and ZBTB41

DIOPT Version :9

Sequence 1:NP_001261357.1 Gene:Asciz / 38381 FlyBaseID:FBgn0035407 Length:388 Species:Drosophila melanogaster
Sequence 2:NP_919290.2 Gene:ZBTB41 / 360023 HGNCID:24819 Length:909 Species:Homo sapiens


Alignment Length:541 Identity:101/541 - (18%)
Similarity:150/541 - (27%) Gaps:253/541 - (46%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MHSEK----------HTPDIRELMPVRE-----HRCERCPSLVFGNLSHYQLHL----------- 39
            :|:.|          |..:.:|.:.:::     .:|:.|.. .|....|.:.|:           
Human   430 LHASKKTLAKHVKRFHPENAQEFISIKKTKSESWKCDICKK-SFTRRPHLEEHMILHSQDKPFKC 493

  Fly    40 ------------RRRHQEVIPPSVIGPIVAFHCPV----------------------EKCIYHVA 70
                        |.:|||...   :||   |.|.:                      .|....:.
Human   494 TYCEEHFKSRFARLKHQEKFH---LGP---FPCDICGRQFNDTGNLKRHIECTHGGKRKWTCFIC 552

  Fly    71 TKGARSFTSLR-------------------------LLRQHYQKSHLDKNYKCLACGGKFLLQHH 110
            .|..|..|:|:                         ..|.|.:..|.||.|:|..||..|:...|
Human   553 GKSVRERTTLKEHLRIHSGEKPHLCSICGQSFRHGSSYRLHLRVHHDDKRYECDECGKTFIRHDH 617

  Fly   111 LEKH-------------QCSK-----------------------------HKCPVCELTYNSKAG 133
            |.||             :|.|                             |:|.||:..:..|:.
Human   618 LTKHKKIHSGEKAHQCEECGKCFGRRDHLTVHYKSVHLGEKVWQKYKATFHQCDVCKKIFKGKSS 682

  Fly   134 LRTHMRRKN----------------------HLVHHESDKVPIPSL---ATWKRLNPQPIPVSAD 173
            |..|.|..:                      |||.| ||..|....   ||:||         .|
Human   683 LEMHFRTHSGEKPYKCQICNQSFRIKKTLTKHLVIH-SDARPFNCQHCNATFKR---------KD 737

  Fly   174 SLTAHSLKTGSDLHPSEEYINNLPSNLAGVTELYAEIPNPEANMPSTLELDTNLPAAEEHILCFL 238
            .|..|.           ::::              ||.:|          |..|..:||.:    
Human   738 KLKYHI-----------DHVH--------------EIKSP----------DDPLSTSEEKL---- 763

  Fly   239 PIMDVSYALEMSSQKLDMETQTEE--DD-----------LNEIRNEVLAPLLRDIETQTPDTRGD 290
                ||..:|.||.....:|:|::  |.           |..:..||..|:.. :..|.|||..|
Human   764 ----VSLPVEYSSDDKIFQTETKQYMDQPKVYQSEAKTMLQNVSAEVCVPVTL-VPVQMPDTPSD 823

  Fly   291 IGTMTDDFPEEQE------------PVAVGSHF-HAYSET------------EPMFDLQTSAHMY 330
            :...|...|....            |.|....| ..|:.|            |.|.|.:..:  |
Human   824 LVRHTTTLPPSSHEILSPQPQSTDYPRAADLAFLEKYTLTPQPANIVHPVRPEQMLDPREQS--Y 886

  Fly   331 TQTCDDLFEELGLSHIQTQTH 351
            ..|...|....|:.:|.|..|
Human   887 LGTLLGLDSTTGVQNISTNEH 907

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AscizNP_001261357.1 C2H2 Zn finger 98..117 CDD:275368 8/31 (26%)
zf-C2H2_2 <116..>143 CDD:289522 10/77 (13%)
C2H2 Zn finger 121..139 CDD:275368 6/17 (35%)
ZBTB41NP_919290.2 BTB_POZ_ZBTB41 66..179 CDD:349535
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 252..344
C2H2 Zn finger 363..383 CDD:275368
C2H2 Zn finger 391..411 CDD:275368
C2H2 Zn finger 424..442 CDD:275368 2/11 (18%)
C2H2 Zn finger 465..485 CDD:275368 5/20 (25%)
C2H2 Zn finger 493..510 CDD:275368 1/16 (6%)
C2H2 Zn finger 520..541 CDD:275368 1/20 (5%)
C2H2 Zn finger 549..569 CDD:275368 4/19 (21%)
C2H2 Zn finger 577..597 CDD:275368 2/19 (11%)
zf-C2H2 603..625 CDD:395048 9/21 (43%)
C2H2 Zn finger 605..625 CDD:275368 8/19 (42%)
C2H2 Zn finger 633..651 CDD:275368 2/17 (12%)
C2H2 Zn finger 670..687 CDD:275368 5/16 (31%)
C2H2 Zn finger 698..718 CDD:275368 3/19 (16%)
C2H2 Zn finger 726..743 CDD:275368 6/25 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

Return to query results.
Submit another query.