DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Asciz and zfp-2

DIOPT Version :9

Sequence 1:	NP_001261357.1	Gene:	Asciz / 38381	FlyBaseID:	FBgn0035407	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_496055.1	Gene:	zfp-2 / 174505	WormBaseID:	WBGene00009448	Length:	422	Species:	Caenorhabditis elegans

Alignment Length:	205	Identity:	47/205 - (22%)
Similarity:	70/205 - (34%)	Gaps:	74/205 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 HRCERCPSLVFGNLSHYQLHLRRRHQEVIPPSVIGPIVAFHC---------------------PV 62
            :||..|.: .|||...||.|::..|.:.      .|...|:|                     |:
Worm   171 YRCTNCKT-YFGNKEVYQRHIQEVHGDA------RPFRCFNCGMRFANKTSMTHHLKDHSLLKPM 228

  Fly    63 EKCIYHVATKGARSFTSLRLLRQHYQKSHLDKNYKCLACGGKFLLQHHLEKHQCSKHKC------ 121
            ..|.|     ..|.|:.|....:|: |.|..:: .|..|...|..:..|..||.:.|..
Worm   229 FSCDY-----CPRIFSKLESKTRHH-KMHFTRS-TCQTCMRFFTTEDALRHHQSTAHPATFDSGP 286

  Fly   122 PVCELTYNSKA--------GLRTHMRRKNHLVHHESDKVPIPSLATWKRLNPQPIPVS------- 171
            |..:|..|.|:        .||.|. :|:.|||              :|::....|.|
Worm   287 PPEDLLPNGKSARYSCSYCNLRFHF-KKDMLVH--------------ERIHTGEKPYSCGYCMKS 336

  Fly   172 ---ADSLTAH 178
               :.:||||
Worm   337 FAQSQALTAH 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Asciz	NP_001261357.1	C2H2 Zn finger	98..117	CDD:275368	6/18 (33%)
		zf-C2H2_2	<116..>143	CDD:289522	9/40 (23%)
		C2H2 Zn finger	121..139	CDD:275368	7/31 (23%)
zfp-2	NP_496055.1	C2H2 Zn finger	173..194	CDD:275368	8/21 (38%)
		C2H2 Zn finger	202..222	CDD:275368	2/19 (11%)
		C2H2 Zn finger	231..251	CDD:275368	7/25 (28%)
		COG5048	<251..>358	CDD:227381	26/112 (23%)
		C2H2 Zn finger	257..278	CDD:275368	6/20 (30%)
		C2H2 Zn finger	302..322	CDD:275368	8/34 (24%)
		C2H2 Zn finger	330..350	CDD:275368	4/17 (24%)
		C2H2 Zn finger	358..374	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000