DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG15812 and ZBTB24

DIOPT Version :9

Sequence 1:NP_523897.2 Gene:CG15812 / 38379 FlyBaseID:FBgn0035405 Length:518 Species:Drosophila melanogaster
Sequence 2:NP_055612.2 Gene:ZBTB24 / 9841 HGNCID:21143 Length:697 Species:Homo sapiens


Alignment Length:558 Identity:102/558 - (18%)
Similarity:184/558 - (32%) Gaps:156/558 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 HSSTIMDIQRSLRNDNQHCEVVLASRDGVRVRAHLFVLSTCSELMRNLLVDVPRGQEATIMLPDI 73
            ||.|::......|.....|::.|.. :.|..|||..:|:..||....:..:.....::..||..:
Human    19 HSDTVLASFEDQRKKGFLCDITLIV-ENVHFRAHKALLAASSEYFSMMFAEEGEIGQSIYMLEGM 82

  Fly    74 RGDLLECMLSFIYMG---------ETSLPSASLPEFLEAINLLGIKSAISFECNPSASPPSVDVE 129
            ..|....:|.|||.|         |..|.:|   :||:..:|  :|:...|:.|.|:..|     
Human    83 VADTFGILLEFIYTGYLHASEKSTEQILATA---QFLKVYDL--VKAYTDFQNNHSSPKP----- 137

  Fly   130 NHSLAVESAKSITGLQIAEAELLDDEEEPHPMVSVPATTLAGSQHQPSHSSRSL-EYIDVYEPPK 193
                        |.|..|.|               |...::..::.|....|.. :.::..:..|
Human   138 ------------TTLNTAGA---------------PVVVISNKKNDPPKRKRGRPKKVNTLQEEK 175

  Fly   194 ITYSIE-----HMDGSSSGNQ-FILTENTGTFTITQSASSLSKIEADETGTSGAEVDLGDDDVDA 252
            ...:.|     .::.|....| |::..::|  .:.:..::..|.|::.|.....|.::   .|:.
Human   176 SELAAEEEIQLRVNNSVQNRQNFVVKGDSG--VLNEQIAAKEKEESEPTCEPSREEEM---PVEK 235

  Fly   253 DLAEDSEEHESQMIDEEFAQADPLMELEAGTEMDDDDDVHDQLVDEEIDDKPRKLGGGKTRIRRP 317
            |...|.:..:.|.....:::    ..:....::.|    :..:.|:|.....:::.|   |.:||
Human   236 DENYDPKTEDGQASQSRYSK----RRIWRSVKLKD----YKLVGDQEDHGSAKRICG---RRKRP 289

  Fly   318 ISAKAVKRLSDC-KPTRIQQFAAL-------KREVKDDIND------------------------ 350
            ...:|  |..|| |..:...|.|:       :|..|  .|:                        
Human   290 GGPEA--RCKDCGKVFKYNHFLAIHQRSHTGERPFK--CNECGKGFAQKHSLQVHTRMHTGERPY 350

  Fly   351 -----ALDLAADAVIIEGLSLQKAADRFDISKTVLWRRVRTNPAYMRNNRERPSLQEAYERLKNG 410
                 :..|.....::|.:||......|...:.         ..|...||:..|    :.|:..|
Human   351 TCTVCSKALTTKHSLLEHMSLHSGQKSFTCDQC---------GKYFSQNRQLKS----HYRVHTG 402

  Fly   411 HSLKSISS--ELQIPMSTLHRHKVRLSAQGRLPNFVSCRKRDNTPKDELR--------------- 458
            |||.....  ...:.:|.|.:| :| :..|..|.......:..|.|..|:               
Human   403 HSLPECKDCHRKFMDVSQLKKH-LR-THTGEKPFTCEICGKSFTAKSSLQTHIRIHRGEKPYSCG 465

  Fly   459 -------DKLAKAVHACLNEGMSQNHAANLFEIPKSTL 489
                   |..||..|..|:.|...      |..|:..|
Human   466 ICGKSFSDSSAKRRHCILHTGKKP------FSCPECNL 497

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15812NP_523897.2 BTB 20..113 CDD:279045 25/101 (25%)
BTB 35..118 CDD:197585 23/91 (25%)
HTH_psq 348..392 CDD:283007 7/72 (10%)
HTH_psq 458..501 CDD:283007 9/54 (17%)
ZBTB24NP_055612.2 BTB 27..133 CDD:306997 27/111 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 131..176 10/76 (13%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 209..254 8/47 (17%)
C2H2 Zn finger 296..316 CDD:275368 5/19 (26%)
COG5048 <321..480 CDD:227381 28/175 (16%)
C2H2 Zn finger 324..344 CDD:275368 1/19 (5%)
C2H2 Zn finger 352..372 CDD:275368 3/19 (16%)
C2H2 Zn finger 380..400 CDD:275368 5/32 (16%)
C2H2 Zn finger 408..428 CDD:275368 4/21 (19%)
C2H2 Zn finger 436..456 CDD:275368 3/19 (16%)
C2H2 Zn finger 464..480 CDD:275368 3/15 (20%)
C2H2 Zn finger 492..512 CDD:275368 2/6 (33%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 652..697
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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