DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15812 and bab2

DIOPT Version :9

Sequence 1:	NP_523897.2	Gene:	CG15812 / 38379	FlyBaseID:	FBgn0035405	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	NP_523879.2	Gene:	bab2 / 44254	FlyBaseID:	FBgn0025525	Length:	1067	Species:	Drosophila melanogaster

Alignment Length:	489	Identity:	97/489 - (19%)
Similarity:	164/489 - (33%)	Gaps:	133/489 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LKWMGHSSTIMDIQRSLRNDNQHCEVVLASRDGVRVRAHLFVLSTCSELMRNLLVDVPRGQEATI 68
            |:|..:.|.:.::...|.......:|.| |.:|..::||..|||.||...:.|..|.| .|...|
  Fly   200 LRWNNYQSNLTNVFDELLQSESFVDVTL-SCEGHSIKAHKMVLSACSPYFQALFYDNP-CQHPII 262

  Fly    69 MLPDIRGDLLECMLSFIYMGETSLPSASLPEFLEAINLLGIK-----SAISFECNPSASPPSV-D 127
            ::.|:....|:.::.|:|.||.::....:...|:....|.|:     ||...|...||.|.|. |
  Fly   263 IMRDVSWSDLKALVEFMYKGEINVCQDQINPLLKVAETLKIRGLAEVSAGRGEGGASALPMSAFD 327

  Fly   128 VENHSLAVESAKSITGLQIAEAELLDDEEEPHPMV---------------------SVPATTLAG 171
            .|:....:.||.:|. .|..:|:..::.:...|.:                     :.|:.:|.|
  Fly   328 DEDEEEELASATAIL-QQDGDADPDEEMKAKRPRLLPEGVLDLNQRQRKRSRDGSYATPSPSLQG 391

  Fly   172 ----------------SQHQPSHSSRSLEYIDVYEPPKITYSIEHMDGSSSGNQFILTENTGTFT 220
                            ||.||...:.|    .:...|..:.:.:.::|.:|....:
  Fly   392 GESEISERGSSGTPGQSQSQPLAMTTS----TIVRNPFASPNPQTLEGRNSAMNAV--------- 443

  Fly   221 ITQSASSLSKIEADETGTSGAEVDLGDDDVDADLA------------EDSEEHESQMIDEE---- 269
            ..|..|..........|.|||.:......|....|            ..:..|.:|.:..:
  Fly   444 ANQRKSPAPTATGHSNGNSGAAMHSPPGGVAVQSALPPHMAAIVPPPPSAMHHHAQQLAAQHQLA 508

  Fly   270 --FAQADPLMELEAGT-----------------------------------EMDDDDDVHDQLVD 297
              .|.|..|....||.                                   ...||.::..::.:
  Fly   509 HSHAMASALAAAAAGAGAAGAGGAGSGSGSGASAPTGGTGVAGSGAGAAVGSHHDDMEIKPEIAE 573

  Fly   298 EEIDDKPRKL------GGGKTRIRRPISAKAVKRLS----------DCKPTR----IQQFAALKR 342
            ...:::..|:      ||..........|.:|...|          .|..|.    :||....:|
  Fly   574 MIREEERAKMIESGGHGGWMGAAAAATGAASVAADSYQYQLQSMWQKCWNTNQQNLVQQLRFRER 638

  Fly   343 -EVKDDINDALDLAADAVIIEGLSLQKAADRFDI 375
             .:|....:|:..|..:|:.|||||.:||.:|||
  Fly   639 GPLKSWRPEAMAEAIFSVLKEGLSLSQAARKFDI 672

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15812	NP_523897.2	BTB	20..113	CDD:279045	27/97 (28%)
		BTB	35..118	CDD:197585	25/87 (29%)
		HTH_psq	348..392	CDD:283007	13/28 (46%)
		HTH_psq	458..501	CDD:283007
bab2	NP_523879.2	BTB	213..309	CDD:279045	26/97 (27%)
		BTB	224..309	CDD:197585	25/86 (29%)
		HTH_psq	645..690	CDD:283007	13/28 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23110
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010