DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG15812 and CG6118

DIOPT Version :9

Sequence 1:NP_523897.2 Gene:CG15812 / 38379 FlyBaseID:FBgn0035405 Length:518 Species:Drosophila melanogaster
Sequence 2:NP_001097806.1 Gene:CG6118 / 41884 FlyBaseID:FBgn0038339 Length:967 Species:Drosophila melanogaster


Alignment Length:525 Identity:99/525 - (18%)
Similarity:190/525 - (36%) Gaps:137/525 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 LKWMGHSSTIMDIQRSLRNDNQHCEVVLASRDGVRVRAHLFVLSTCSELMRNLLVDVPRGQEATI 68
            |.|......:.....||:.|.:..:|.:|: .|...:||..|||.||...:.:.::.| .....:
  Fly   395 LSWNNFHGNMCRGFHSLQKDEKMVDVTIAA-GGKIFKAHKLVLSVCSPYFQQIFLENP-SSHPIL 457

  Fly    69 MLPDIRGDLLECMLSFIYMGETSLPSASLPEFL---EAINLLGIKSAISFECNPS--ASPPSVDV 128
            ::.|:....:..:|.|:|.|:.::....||.||   ||:.:.|:.:..:.:.:.|  :||...|.
  Fly   458 LMADVEASHMAGLLDFMYSGQVNVKYEDLPVFLKVAEAMKIKGLHTEKNLDSDASDISSPHESDG 522

  Fly   129 E-------NHSLAVESAKSITGLQIAEAELLDDEEEPHPMVS----VPATTLAGSQHQPSHSSRS 182
            .       .||:.:.|..: .|...|.:   ..:..|.|.::    .|....:|....|:::. .
  Fly   523 TECRYERGTHSVNITSGHA-AGYGGAPS---SQQSSPSPSLNGPNRCPTPLSSGGSGNPNYAG-F 582

  Fly   183 LEYIDVYEPPKITYSIEHM--------DGSSSGNQFILTENTGTFTITQS-ASSLSKIEADETGT 238
            .|:|    ..|.|.:...|        :.:||.|...|..:.|:..:|:: ::|.:.::|     
  Fly   583 REHI----KSKATLAETFMKNLNRNNNNNNSSNNYNHLGGSNGSLNLTEADSNSFAILQA----- 638

  Fly   239 SGAEVDLGDDDVDADLAEDSEEHESQMIDEEFAQADPLME----LEAGTEMDDDDDVHDQLVDEE 299
                                  :..:|:|....|...|.:    :...||:              
  Fly   639 ----------------------NSKKMLDSARKQHKYLAKRKILMHYNTEL-------------- 667

  Fly   300 IDDKPRKLGGGKTRIRRPISAKAVKRLSDCKPTRIQQFAALKREVKDDINDALDLAADAVIIEGL 364
                     ||:.|:      |.::|  |..|:..|.        .|.:|:....|.|.::    
  Fly   668 ---------GGEKRL------KEMER--DRYPSAEQH--------DDALNNNHSHAQDNIM---- 703

  Fly   365 SLQKAADRFDISKTVLWRRVRTNPAYMRNNRERPSLQEAYERLKNGHSLKSISSELQIPMSTLHR 429
                    ..|..|::   .:|.|....||..:..|.|::....|.::.::.||......|:...
  Fly   704 --------EPIITTIV---PQTPPPSTHNNNFKIRLVESHHLTNNSNNNQNQSSNNNNSSSSPQS 757

  Fly   430 HKVRLSAQG----RLPNFVSCRKRDNTP------------KDELRDKLAKAVHACLNEGMSQNHA 478
            :......:.    ::||....|.|:.||            |.|::.:|:.|.:...|.|.....|
  Fly   758 NDCNNDEEALNLVQIPNANGSRNREATPTCATPTPDIQLIKREVKTELSPAENLSNNNGHDDEMA 822

  Fly   479 ANLFE 483
            ...|:
  Fly   823 GAGFD 827

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15812NP_523897.2 BTB 20..113 CDD:279045 25/95 (26%)
BTB 35..118 CDD:197585 21/85 (25%)
HTH_psq 348..392 CDD:283007 7/43 (16%)
HTH_psq 458..501 CDD:283007 6/26 (23%)
CG6118NP_001097806.1 Myb_DNA-bind_4 20..97 CDD:290549
BTB 408..508 CDD:279045 26/101 (26%)
BTB 419..510 CDD:197585 23/92 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1229475at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR23110
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
33.020

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