DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15812 and lov

DIOPT Version :9

Sequence 1:	NP_523897.2	Gene:	CG15812 / 38379	FlyBaseID:	FBgn0035405	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	NP_611994.3	Gene:	lov / 38007	FlyBaseID:	FBgn0266129	Length:	1143	Species:	Drosophila melanogaster

Alignment Length:	469	Identity:	99/469 - (21%)
Similarity:	166/469 - (35%)	Gaps:	128/469 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LKWMGHSSTIMDIQRSLRNDNQHCEVVLASRDGVRVRAHLFVLSTCSELMRNLLVDVPRGQEATI 68
            |:|..|.:.|:....:|.......:|.|...: ..:|||..|||.||...:.:..:.| .:...|
  Fly   117 LRWNNHQNHILRAFDALLKTKTLVDVTLVCAE-TSIRAHKMVLSACSPFFQRVFAETP-CKHPVI 179

  Fly    69 MLPDIRGDLLECMLSFIYMGETSLPSASLPEFLEAINLLGIKSAISFEC-----NPSASPPSVDV 128
            :|.|.||.:::.::.|:|.||.|:|...|...::|...|.::..:....     .|:|||....:
  Fly   180 VLKDFRGWVVQAIVDFMYRGEISVPQQRLQTLIQAGESLQVRGLVESSVPEHTPTPAASPDDFGM 244

  Fly   129 ENHSLAVESAKSITGLQIAEAELLDDEEEPHPMVS--------VPATTLAGS-----------QH 174
            .:.|:...:.                |:|...||.        :|:..|.|:           :.
  Fly   245 LDTSMLSSTF----------------EDECPTMVRPSKGGKLLMPSARLFGNASSAIAALGLRRK 293

  Fly   175 QPSHSSRSLEYIDVYEPPKITYSIEHMDGSS-------------SGNQFILTENTGTFTITQS-A 225
            :...|.|.||            |.:.:.|||             ||      :....||:.:: |
  Fly   294 REQESDRDLE------------SDQELGGSSPMPRRKQARPRRRSG------DVPHDFTLNKTDA 340

  Fly   226 SSLSKI--------------EADETGTSGAEVDLGDDDVDADLAEDSEEHESQMIDEEFAQADPL 276
            .||..:              ||.:...|..|.:.........|.|.::|.:| |.:|...|...|
  Fly   341 ESLQTVIKHELLERAERDQEEAPDQDNSQGEAEKISSSPAKTLVERAKEQKS-MKEEGSDQPRSL 404

  Fly   277 MELEAGTEMDDDDDVHDQLVDEEIDDKPRKLGGGKTRIRRPISAKAVKRLSDCKPTRIQQFAALK 341
            .|.....|:||:|| .||..:||.:....:|......:||..:|.|...            ||:.
  Fly   405 NENHHQLELDDEDD-DDQDHEEEEEQDIEELIHTTNELRRQAAAAAANA------------AAMS 456

  Fly   342 REVKDDINDALDLAADAVIIEGLSLQKAADRFDISKTVLWRRVRTNPAYM----RNNRERPSLQE 402
            ......::|..:                    |:..|...:.:.:.|:..    .||.....||:
  Fly   457 PNPSPCLSDGPE--------------------DLCTTKKGKELISGPSSSADCESNNNNSSKLQD 501

  Fly   403 AYERLKNGHSLKSI 416
            ..:|:.  .|||.|
  Fly   502 NNQRIM--LSLKDI 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15812	NP_523897.2	BTB	20..113	CDD:279045	26/92 (28%)
		BTB	35..118	CDD:197585	23/87 (26%)
		HTH_psq	348..392	CDD:283007	4/47 (9%)
		HTH_psq	458..501	CDD:283007
lov	NP_611994.3	BTB	130..225	CDD:279045	26/96 (27%)
		BTB	141..226	CDD:197585	25/86 (29%)
		HTH_psq	791..834	CDD:283007
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1229475at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23110
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.020