DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG15812 and KLHL30

DIOPT Version :9

Sequence 1:NP_523897.2 Gene:CG15812 / 38379 FlyBaseID:FBgn0035405 Length:518 Species:Drosophila melanogaster
Sequence 2:NP_940984.3 Gene:KLHL30 / 377007 HGNCID:24770 Length:578 Species:Homo sapiens


Alignment Length:317 Identity:67/317 - (21%)
Similarity:113/317 - (35%) Gaps:83/317 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 HLKWMGHSSTIMDIQRSLRNDNQHCEVVLASRDGVRVRAHLFVLSTCSELMRNLLV-DVPRGQEA 66
            ||.  .|:..::|..:.||:..:..:|.|.. .|..:..|..:|:..|.....:.. |......|
Human    11 HLP--SHAQDMLDGLQRLRSQPKLADVTLLV-GGRELPCHRGLLALSSPYFHAMFAGDFAESFSA 72

  Fly    67 TIMLPDIRGDLLECMLSFIYMGETSL-----------------PSAS------LPEFLEAINLLG 108
            .:.|.|:...::..::.|:|.|..::                 ||..      |.:.|:|.|.||
Human    73 RVELRDVEPAVVGQLVDFVYTGRLTITQGNVEALTRTAARLHFPSVQKVCGRYLQQQLDAANCLG 137

  Fly   109 IKSAISFECNPSASPPSVDVENHSLAVESAKSITGL-QIAEAELLDDEEEPHPMVSVP----ATT 168
            |       |...        |...|...:||:...| :..||...:||     .:.:|    .|.
Human   138 I-------CEFG--------EQQGLLGVAAKAWAFLRENFEAVAREDE-----FLQLPRERLVTC 182

  Fly   169 LAGS--QHQPSHS--SRSLEYIDVYEP-------PKITYSIEHMDGSSSGNQFILTENTGTFTIT 222
            |||.  |.||..|  ...:.::. ::|       |:: .|:.|:|.....            .:.
Human   183 LAGDLLQVQPEQSRLEALMRWVR-HDPQARAAHLPEL-LSLVHLDAVPRP------------CVQ 233

  Fly   223 QSASSLSKIEADETGTSGAEVDLGDDDVDADLAEDSEE----HESQMIDEEFAQADP 275
            |..:|...|:  |:....|.:..|.|.....|.:..||    ...|.::||.|..:|
Human   234 QLLASEPLIQ--ESEACRAALSQGHDGAPLALQQKLEEVLVVVGGQALEEEEAGEEP 288

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15812NP_523897.2 BTB 20..113 CDD:279045 24/116 (21%)
BTB 35..118 CDD:197585 20/106 (19%)
HTH_psq 348..392 CDD:283007
HTH_psq 458..501 CDD:283007
KLHL30NP_940984.3 BTB 23..127 CDD:279045 17/104 (16%)
PHA03098 29..550 CDD:222983 61/297 (21%)
BACK 135..237 CDD:285009 28/135 (21%)
Kelch 1 270..326 5/19 (26%)
KELCH repeat 318..363 CDD:276965
Kelch 2 327..377
Kelch 328..377 CDD:128874
Kelch_1 366..407 CDD:279660
KELCH repeat 367..409 CDD:276965
Kelch 3 378..422
KELCH repeat 412..454 CDD:276965
Kelch 4 424..471
KELCH repeat 461..498 CDD:276965
Kelch 5 473..513
KELCH repeat 503..550 CDD:276965
Kelch 6 514..563
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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