DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG15812 and ab

DIOPT Version :9

Sequence 1:NP_523897.2 Gene:CG15812 / 38379 FlyBaseID:FBgn0035405 Length:518 Species:Drosophila melanogaster
Sequence 2:NP_476562.1 Gene:ab / 34560 FlyBaseID:FBgn0264442 Length:904 Species:Drosophila melanogaster


Alignment Length:545 Identity:114/545 - (20%)
Similarity:189/545 - (34%) Gaps:145/545 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 LKWMGHSSTIMDIQRSLRNDNQHCEVVLASRDGVRVRAHLFVLSTCSELMRNLLVDVPRGQEATI 68
            |||....|:|:...|.||::....:|.||. |.....||..|||.||...|.||...| .:...:
  Fly    80 LKWNDFQSSILSSFRHLRDEEDFVDVTLAC-DERSFTAHKVVLSACSPYFRRLLKANP-CEHPIV 142

  Fly    69 MLPDIRGDLLECMLSFIYMGETSLPSASLPEFLEAINLLGIK----------------SAISFEC 117
            :|.|:|.|.:|.:|||:|.||.::....||:||:..:||.|:                :|:|.  
  Fly   143 ILRDVRCDDVENLLSFMYNGEVNVSHEQLPDFLKTAHLLQIRGLADVNGGYPYSKALSAALSH-- 205

  Fly   118 NPSASPPSVDVENHSLAVESAKSITGLQIAEAELLDDEEEPHPMVSVPATTLAGS---QHQPSHS 179
            |.|.:..:....|:||:..:..:....:.:....:.....|: ..|......:.|   .|..||:
  Fly   206 NSSNNNNNNSSSNNSLSNNNNNNNNNAESSNHNKISSYLSPN-QTSAACNNSSNSNSNNHSSSHN 269

  Fly   180 SRSLEYID-------------VYEPPKITYSIEHMDGSSSGNQFILTENTGTFTITQSASSLSKI 231
            :.|...|.             ...||.:|.|......:::.:...........|...:.||.|..
  Fly   270 NSSSNNISGSLNSSLNSPFSAPQIPPPVTASSAAAAAAAAASLTAAVAAAAAATAASAGSSSSAA 334

  Fly   232 EADETGT--------------------------SGAEVDLGDDD---------------VDADL- 254
            ....:||                          |....|:|:.:               ..||| 
  Fly   335 SGQTSGTPAIQELKASSAASPVRNPNPNPSKASSSNHWDMGEMEGSRKSHLTPPPQKRIKSADLF 399

  Fly   255 -AEDSEEHESQMIDEEF--AQADPLMELEAGTEMDDDD----DVHDQLVDEEIDDKPRKLGGGKT 312
             |:.....|..::|.||  |...||....:|.:...|.    ::.:.|:.:.:::...:....|.
  Fly   400 RAQHGISPERLLLDREFPVAGQHPLTRNRSGRDTSKDRERNLELRESLLGQALENSNGQQANPKH 464

  Fly   313 RIRRPISAKAVKRLSDCKPT-----------------RIQQFAALKREVKDDINDALDLAADAVI 360
            .:.:  ||......||.:|:                 |...|.          |..|.|..    
  Fly   465 ELGQ--SAGEDSNSSDTEPSDRGDGQHDGTLDGIDNQRSHSFP----------NAFLGLQG---- 513

  Fly   361 IEGLSLQKAADRFD-ISKTVLWRRVR-TNPAYMRNNRERPSLQEAYERLKNGHSLKS-------- 415
            |.||....:....| :|:..|..||| |:|      |..|...:.|   ::.|:|::        
  Fly   514 IPGLLPGPSGINSDFVSRRSLEMRVRATDP------RPCPKCGKIY---RSAHTLRTHLEDKHTV 569

  Fly   416 -------ISSELQIPMSTLHRHKVR 433
                   :...:....::||.|..|
  Fly   570 CPGYRCVLCGTVAKSRNSLHSHMSR 594

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15812NP_523897.2 BTB 20..113 CDD:279045 35/108 (32%)
BTB 35..118 CDD:197585 32/98 (33%)
HTH_psq 348..392 CDD:283007 14/45 (31%)
HTH_psq 458..501 CDD:283007
abNP_476562.1 BTB 93..189 CDD:279045 36/97 (37%)
BTB 104..189 CDD:197585 33/86 (38%)
zf-Di19 545..597 CDD:283297 8/53 (15%)
C2H2 Zn finger 546..567 CDD:275371 4/23 (17%)
C2H2 Zn finger 575..596 CDD:275371 4/20 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1229475at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR23110
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
33.020

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