DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15812 and Zbtb24

DIOPT Version :9

Sequence 1:	NP_523897.2	Gene:	CG15812 / 38379	FlyBaseID:	FBgn0035405	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	NP_700447.2	Gene:	Zbtb24 / 268294	MGIID:	3039618	Length:	710	Species:	Mus musculus

Alignment Length:	341	Identity:	69/341 - (20%)
Similarity:	118/341 - (34%)	Gaps:	81/341 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 HSSTIMDIQRSLRNDNQHCEVVLASRDGVRVRAHLFVLSTCSELMRNLLVDVPRGQEATIMLPDI 73
            ||.|::......|.....|::.|.. :.|..|||..:|:..||....:..:.....::..||..:
Mouse    19 HSDTVLASLEDQRKKGFLCDITLIV-ENVHFRAHKALLAASSEYFSMMFAEEGEIGQSIYMLEGM 82

  Fly    74 RGDLLECMLSFIYMG------ETSLPSASLPEFLEAINLLGIKSAISFECNPSA-SPPSVDVENH 131
            ..|....:|.|||.|      :|:....:..:||:..:|  :|:...|:.|.|| .||:::....
Mouse    83 VADTFGILLEFIYTGYLHASEKTTEQILATAQFLKVYDL--VKAYADFQDNHSAPKPPALNCTGT 145

  Fly   132 SLAVESAK-------------SITGLQIAEAELLDDEEEPHPMVSVPATTLAGSQHQPSHSSRSL 183
            .:.|.|.|             ...|||...:||..:.|                          |
Mouse   146 PVVVISNKKNDPLKRKRGRPRKANGLQEGRSELAAEGE--------------------------L 184

  Fly   184 EYIDVYEPPKITYSIEHMDGSSSGNQFILTENTGTFTITQSASSLSKIEADETGTSGAEVDLGDD 248
            :.       ::..|:::.      ..|:..|........|:........|.|.| |..||....|
Mouse   185 QL-------RVNNSVQNR------QNFVFKEEDSVKLSEQTPEDKESEPAGEPG-SVEEVPAEKD 235

  Fly   249 DVDADLAEDSEEHESQMIDEEFAQADPLMELEAGTEMDDDDDVHDQLVDEEIDDKPRKLGGGKTR 313
            :.....|.|.:|.:|:.......::..|.:.:.   :.|:||          ....::|.|.|.|
Mouse   236 ENFDPKAGDGQESQSRCSRRRIRRSVKLKDYKL---LGDEDD----------QSTAKRLCGRKKR 287

  Fly   314 IRRPISAKAVKRLSDC 329
            ...|.:     |..||
Mouse   288 SSGPEA-----RCKDC 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15812	NP_523897.2	BTB	20..113	CDD:279045	23/98 (23%)
		BTB	35..118	CDD:197585	21/88 (24%)
		HTH_psq	348..392	CDD:283007
		HTH_psq	458..501	CDD:283007
Zbtb24	NP_700447.2	BTB	27..128	CDD:279045	23/103 (22%)
		BTB	38..133	CDD:197585	23/97 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	134..176		9/41 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	202..256		13/54 (24%)
		C2H2 Zn finger	295..315	CDD:275368	2/4 (50%)
		zf-H2C2_2	308..332	CDD:290200
		COG5048	<320..479	CDD:227381
		C2H2 Zn finger	323..343	CDD:275368
		zf-H2C2_2	335..360	CDD:290200
		C2H2 Zn finger	351..371	CDD:275368
		zf-H2C2_2	363..388	CDD:290200
		C2H2 Zn finger	379..399	CDD:275368
		COG5048	406..>563	CDD:227381
		C2H2 Zn finger	407..427	CDD:275368
		zf-H2C2_2	420..443	CDD:290200
		C2H2 Zn finger	435..455	CDD:275368
		zf-H2C2_2	447..471	CDD:290200
		C2H2 Zn finger	463..479	CDD:275368
		zf-H2C2_2	477..500	CDD:290200
		C2H2 Zn finger	491..511	CDD:275368
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	651..676
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910