DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15812 and eor-1

DIOPT Version :9

Sequence 1:	NP_523897.2	Gene:	CG15812 / 38379	FlyBaseID:	FBgn0035405	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	NP_001367921.1	Gene:	eor-1 / 177249	WormBaseID:	WBGene00001324	Length:	909	Species:	Caenorhabditis elegans

Alignment Length:	428	Identity:	75/428 - (17%)
Similarity:	137/428 - (32%)	Gaps:	143/428 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 LLECMLSFIYMGETSLPSASLPE-----------------------FLEAINLLGIKSAISFECN 118
            :.|..|:::|.|...:..:|:.|                       :|:|.|.|.|::.......
Worm    90 VFELFLNYMYSGTVIIDRSSVSELLRFANNFLIVKLKVYCAAYLDRYLDAANCLSIRTLAQRYNL 154

  Fly   119 PSASPPSVDV--ENHSLAVESAKSITGLQIAE-AELLDDEEEPHPMVSVPATT------------ 168
            |.....:.|.  .|.:..:..::.|.|....: ..|:.|   |..:..:.:.|
Worm   155 PGLVKSATDYFDSNLNRCLLESRDIIGYTYTQLTRLIGD---PKYVDCITSDTYLKLIVRWVGEE 216

  Fly   169 ----------LAGSQHQPSHSSRSLEYIDVYEPPKITYSIEHMDGSSSGNQFILTE--NTGTFTI 221
                      |..|......|:.:||::..|.|         :...|..::|:|..  .|....:
Worm   217 VSKREEIFRLLLESCEFREVSADTLEFLLDYSP---------LLSKSQKSRFLLLHVMETNNMLM 272

  Fly   222 TQSASSLSKIEADETGTSGAEVDLGDDDVDADLAEDSEEHESQMIDEEFAQADPLMELEAGTEMD 286
            .:.::.||              .|....||..:..|..:.|..:.|...::.||
Worm   273 EKYSTQLS--------------SLRQKIVDLPILHDPSQFEDDIYDSSDSEEDP----------- 312

  Fly   287 DDDDVHD------QLVDEEIDDKPR-------KLGGGKTRIRRPISAKAVKR--LSDCKPTRIQQ 336
             ||.:.|      |:|:...|...|       :.|..|.|::||   |.:|:  |....|....:
Worm   313 -DDYIADGHPTSAQVVEYGNDVNNRLKMKIAFQPGNEKKRLKRP---KGMKKHHLHPIPPINATE 373

  Fly   337 FAALKREVKDDINDALDLAADAVIIEGLSLQKAADRFDISKTVLWRRVRTNPAYMRNNRERPSLQ 401
            ..::....:|:|:......:    :||.......|..|             |....:..::|.
Worm   374 NESIPWIDEDEIDGVYATCS----LEGCHTYGPVDNLD-------------PDDCEDEEDQPD-- 419

  Fly   402 EAYERLKNGHS------LKSISSELQIPMSTLHRHKVR 433
                  :||.|      |::.:.||      |.:||.|
Worm   420 ------ENGPSTCIFCGLRTANEEL------LEKHKAR 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15812	NP_523897.2	BTB	20..113	CDD:279045	11/58 (19%)
		BTB	35..118	CDD:197585	11/63 (17%)
		HTH_psq	348..392	CDD:283007	6/43 (14%)
		HTH_psq	458..501	CDD:283007
eor-1	NP_001367921.1	PHA03098	34..>229	CDD:222983	21/141 (15%)
		BTB_POZ_ZBTB_KLHL-like	41..118	CDD:349497	6/27 (22%)
		C2H2 Zn finger	455..475	CDD:275368
		zf-C2H2_8	<481..527	CDD:406359
		C2H2 Zn finger	483..503	CDD:275368
		C2H2 Zn finger	511..531	CDD:275368
		C2H2 Zn finger	541..561	CDD:275368
		C2H2 Zn finger	569..589	CDD:275368
		C2H2 Zn finger	601..618	CDD:275368
		C2H2 Zn finger	626..646	CDD:275368
		zf-H2C2_2	638..663	CDD:404364
		zf-H2C2_5	652..676	CDD:404746
		C2H2 Zn finger	654..674	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910