DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15812 and AgaP_AGAP008959

DIOPT Version :9

Sequence 1:	NP_523897.2	Gene:	CG15812 / 38379	FlyBaseID:	FBgn0035405	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	XP_319710.4	Gene:	AgaP_AGAP008959 / 1279925	VectorBaseID:	AGAP008959	Length:	489	Species:	Anopheles gambiae

Alignment Length:	400	Identity:	76/400 - (19%)
Similarity:	122/400 - (30%)	Gaps:	140/400 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 AHLFVLSTCSELMRNLLVDVPRGQ-EATIMLPDIRGDLLECMLSFIYMGETSLPSASLPEFLEAI 104
            ||..:|:.||:...:|....|.|. :..:||.....|.:..:|.|:|.||..:...:|..||:|.
Mosquito     5 AHKVILAACSKNFADLFERAPVGTGQICVMLEATSADNMHALLEFMYKGEVHVSQKALESFLKAA 69

  Fly   105 NLLGIK--SAISFEC-------------------------------NPSASP--------PSVDV 128
            ..|.:.  ..|...|                               .||.||        ||..:
Mosquito    70 ENLQVSHTRGIDLRCEDEAVITPAICVCTGQRTHYRARSFASANASQPSQSPFHGPPNDLPSPAI 134

  Fly   129 ---ENHSLA-----------------VESAKS-----------------ITGLQIAEAELLDDEE 156
               :.:||:                 |.||.|                 .||...:.|:.....:
Mosquito   135 RRQQRNSLSSSLESINRAVKRETDSIVGSASSGGNGSSHGSGGGAGAGGATGNAGSGADRGSGND 199

  Fly   157 EPH----------------------------PMVSV-----PATTLAGSQHQPSHSSRSLEYIDV 188
            ..:                            |..|.     |::.|.||......|.||    ..
Mosquito   200 RGNRGNDRGGESGGVGGGGGGGGGGGGGGNTPASSFSPYLQPSSYLPGSYENRKRSLRS----PF 260

  Fly   189 YEPPKITYSIEHMDGSSSGNQFILTENTGTFTITQSASSLSKIEADETGTSGAEVDLGDDDVDAD 253
            ||..:.|......||.:|.........:..:..:.|.||.:..|||...|            |.|
Mosquito   261 YEHQEATRDSVLRDGKASAGNGSPVSGSKNYRPSSSGSSATPTEADTIHT------------DRD 313

  Fly   254 LAEDSEEHESQMIDEEFAQAD-PLMELEAGTEMD-DDDDVHDQLVDEEIDDKPR---KLGGGKTR 313
            ..:.|..:|:..........: |:    :...|| ::.:.|:..||.::..:.|   :.|....|
Mosquito   314 SPQQSNRYENHSPSTTHGHGNGPV----SSNTMDREERNDHNGSVDHKVKHESREGNEAGAEDLR 374

  Fly   314 IR---RPISA 320
            ::   |||.:
Mosquito   375 VKMEMRPIQS 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15812	NP_523897.2	BTB	20..113	CDD:279045	21/74 (28%)
		BTB	35..118	CDD:197585	23/110 (21%)
		HTH_psq	348..392	CDD:283007
		HTH_psq	458..501	CDD:283007
AgaP_AGAP008959	XP_319710.4	BTB	1..86	CDD:197585	23/80 (29%)
		BTB	<3..76	CDD:279045	21/70 (30%)
		C2H2 Zn finger	437..458	CDD:275368
		C2H2 Zn finger	465..482	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1229475at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920