DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15812 and AgaP_AGAP003685

DIOPT Version :9

Sequence 1:	NP_523897.2	Gene:	CG15812 / 38379	FlyBaseID:	FBgn0035405	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	XP_313467.4	Gene:	AgaP_AGAP003685 / 1274359	VectorBaseID:	AGAP003685	Length:	499	Species:	Anopheles gambiae

Alignment Length:	501	Identity:	82/501 - (16%)
Similarity:	145/501 - (28%)	Gaps:	188/501 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LKWMGHSSTIMDIQRSLRNDNQHCEVVLASRDGVRVRAHLFVLSTCSELMRNLLVDVPRGQEATI 68
            |.|.|....:.....||:.|.|..:|.:|: .|...:||..|||.||...:.:.::.| .|...:
Mosquito     7 LSWRGFHGNMCKGFHSLQRDGQMVDVTIAA-GGKIFKAHKLVLSVCSPYFQKIFLEHP-SQHPIL 69

  Fly    69 MLPDIRGDLLECMLSFIYMGETSLPSASLPEFLEAINLLGIKSAISFECNPSASPPSVDVEN-HS 132
            .:.|:....:..:|.|:|.|:.::....||.||:....|.:|.......|.|........:: |:
Mosquito    70 FMTDVNSHHMAGLLDFMYSGQVNVKYEDLPNFLKVAEALQVKGLHGESTNDSEERDYQQQQHQHA 134

  Fly   133 LAVESAKSITG----------------------------------------LQIAEAELLDDEEE 157
            |.::..:.:..                                        ||:|:.:.....::
Mosquito   135 LRLQEQQRLYHQQQQQQHQQQLHQQQQQQQQQQQQQQQQQQQKLAQQRQQLLQVAQQQAHAQAQQ 199

  Fly   158 PH----------------------------PMVSVPATTLAGSQHQPSHSSRSL----------- 183
            .|                            ...:..|..:|..|.|..|...:.
Mosquito   200 QHQQQQQQQQQQQQQQQQQQQQAAAAAAAQQQAAAVAAAVAHQQQQFQHHRNNFKELMKAKHAAA 264

  Fly   184 ------EYIDVYEPPKITYSIEHMDGSSSGNQFILTEN--------------------------- 215
                  :|::     ....:..:.:.||:||...|..|
Mosquito   265 AVVLNEDYLN-----NNASNANNNNNSSNGNNGNLASNGNANGPLSPYASKKMLDTQKYQKYYSK 324

  Fly   216 -----------------TGTFTITQSASSLSKIEA---DETGTSGAEVDLGDDDVDADLAEDSEE 260
                             .|...:.|:|::.:.:..   :.|.|:|....  ||:.........::
Mosquito   325 RKLVQQYEQEMRAEKRKLGIEDVIQAAAAANALNLRLNNGTPTNGGTST--DDEQQQQQQHQQQQ 387

  Fly   261 HESQMIDEEFAQADPLM-----------ELEAGTEMDDD---------------------DDV-- 291
            |:.|  ..:..|..|::           :.:.|.|:|.|                     ||.
Mosquito   388 HQQQ--QHQHGQQTPVLLQNIKSEPQYDDEDEGMEVDQDNNNSLNAANANTAHNNNNNNEDDYYG 450

  Fly   292 -HDQLVDEEIDDKPRKLGGGKTRIRRPISAKAVKRLSD-CKPTRIQ 335
             |||.|        ...|.|||.....:....|.:.|| |..|..|
Mosquito   451 QHDQGV--------ITTGNGKTIKHSILEPNIVLKQSDECLTTNNQ 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15812	NP_523897.2	BTB	20..113	CDD:279045	26/92 (28%)
		BTB	35..118	CDD:197585	21/82 (26%)
		HTH_psq	348..392	CDD:283007
		HTH_psq	458..501	CDD:283007
AgaP_AGAP003685	XP_313467.4	BTB	20..113	CDD:279045	27/94 (29%)
AgaP_AGAP003685	XP_313467.4	BTB	31..113	CDD:197585	23/83 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1229475at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920