DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15812 and AgaP_AGAP002303

DIOPT Version :9

Sequence 1:	NP_523897.2	Gene:	CG15812 / 38379	FlyBaseID:	FBgn0035405	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	XP_312667.5	Gene:	AgaP_AGAP002303 / 1273665	VectorBaseID:	AGAP002303	Length:	466	Species:	Anopheles gambiae

Alignment Length:	524	Identity:	112/524 - (21%)
Similarity:	190/524 - (36%)	Gaps:	145/524 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LKWMGHSSTIMDIQRSLRNDNQHCEVVLASRDGVRVRAHLFVLSTCSELMRNLLVDVPRGQEATI 68
            ::|..|..::......:|..:...:|.||. :|.:|..|..||:.||....|||.:.|......|
Mosquito    14 VRWNSHLGSLGAAFPQVRKPSPFVDVTLAC-EGHQVHCHRLVLAACSTYFENLLGENPCKHPIII 77

  Fly    69 MLPDIRGDLLECMLSFIYMGETSLPSASLPEFLEAINLLGIKSAISFECNPSASPPSVDVENHSL 133
            :..||:...::.::.|:|.||.::..|.||:.::...:|.|:..    |...|          :|
Mosquito    78 LPRDIKLWAIQALVDFMYKGEVNVSQAGLPDLMKCAEVLKIRGL----CGSDA----------AL 128

  Fly   134 AVESAKSITGLQIAEAELLDDEEEPHPMVSVPATTLAGSQHQPSHSSRSLEYIDVYEPPKITYSI 198
            .:....|.:|....:.:                      ||..::||      |..||      :
Mosquito   129 NLNQVHSPSGSHQYQQQ----------------------QHSSANSS------DAGEP------V 159

  Fly   199 EHMDGSSSGNQFILTENTGTFTITQSASSLSKIEADETGTSGAEVDLGD----DDVDADLAEDSE 259
            ||...::..::       |::.......|.|........:||.:..|.:    ..:||.:|....
Mosquito   160 EHAGATARASE-------GSYAGRHGGQSQSARMQQSNASSGPKRQLLNSLNLQPIDAGIALPHH 217

  Fly   260 EHESQMIDEEFAQADPLMELEAGTEM---------DDDDDVHDQLVDEEIDDKPRKLGGGKTRIR 315
            .|..|  :|:...:|   ..|:|.||         |:||....|..|||      :||...|.
Mosquito   218 HHHQQ--NEDGVHSD---NGESGNEMCIKTEDLIIDEDDSGSRQCGDEE------ELGMDSTD-- 269

  Fly   316 RPISAKAVKRLSDCKPTRIQQFAALKREVKDDINDALDLAADAVIIEGLSLQKAADRFDISKTVL 380
                    |..||..    .:||......:.::|.......|.                   :..
Mosquito   270 --------KTGSDLP----SEFALANVTCEYELNTQPQAPQDT-------------------STA 303

  Fly   381 WRRVRTNPAYMRNNRERPSLQEAYERLKNGHSLKSISSELQIPMSTLHRHKVRLSAQGRLPNFVS 445
            .||||         |....||:|.|.:..|.:.:::|.:..||:||:..:..|   :|.||.
Mosquito   304 GRRVR---------RSEELLQQAAEYVSRGETFQNVSLKFDIPISTIRFYMAR---KGILPR--- 353

  Fly   446 CRKRDNT---PKDELRDKLAKAVHACLNEGMSQNHAANLFEIPKSTLWRHLQRRTTSQNKKVKKE 507
             |||..|   |.......:..||     :.|:.:..::.  ||:.||      |...|.::.:::
Mosquito   354 -RKRGRTAMFPCSVSNRPILAAV-----DMMAPSPTSSF--IPQPTL------RDQQQQQQYRQQ 404

  Fly   508 LKAN 511
            |..|
Mosquito   405 LSEN 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15812	NP_523897.2	BTB	20..113	CDD:279045	27/92 (29%)
		BTB	35..118	CDD:197585	23/82 (28%)
		HTH_psq	348..392	CDD:283007	6/43 (14%)
		HTH_psq	458..501	CDD:283007	8/42 (19%)
AgaP_AGAP002303	XP_312667.5	BTB	31..121	CDD:279045	27/90 (30%)
AgaP_AGAP002303	XP_312667.5	BTB	38..121	CDD:197585	26/83 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1229475at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920