DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15812 and AgaP_AGAP010355

DIOPT Version :9

Sequence 1:	NP_523897.2	Gene:	CG15812 / 38379	FlyBaseID:	FBgn0035405	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	XP_311585.4	Gene:	AgaP_AGAP010355 / 1272684	VectorBaseID:	AGAP010355	Length:	874	Species:	Anopheles gambiae

Alignment Length:	482	Identity:	98/482 - (20%)
Similarity:	183/482 - (37%)	Gaps:	99/482 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LKWMGHSSTIMDIQRSLRNDNQHCEVVLASRDGVRVRAHLFVLSTCSELMRNLLVDVPRGQEATI 68
            |:|..|.:.|:....:|.......:|.|...: ..:|||..|||.||...:.:..|.| .:...|
Mosquito     9 LRWNNHQNHILRAFDTLLQTKTLVDVTLVCAE-TSIRAHKVVLSACSPFFQRVFSDTP-CKHPVI 71

  Fly    69 MLPDIRGDLLECMLSFIYMGETSLPSASLPEFLEAINLLGIKSAISFECNPSASPPSVDVENHSL 133
            :|.|.||.:::.::.|:|.||.|:|...|...::|...|.::..:......:...|:...|:.||
Mosquito    72 VLKDFRGWVVQAIVDFMYRGEISVPQERLSVLIQAGESLQVRGLVDHPVAANTPTPAESPEDFSL 136

  Fly   134 AVESAKSITGLQIAEAELLDDEE----EPHPMVSVPATTLAGSQHQPSHSSRSLEYIDVYEPPKI 194
            ...|..|.|...:.......:.:    ..|.  :.|::.::|      ::|:.|....|:..|.|
Mosquito   137 LEGSLISPTSPSLPSPNFQTNHQSGQLRHHS--TTPSSLISG------NASKLLLPPQVFADPSI 193

  Fly   195 TYSIEHMDGSSSGNQFILTENTGTFTITQSASSLSKIEADETGTSGAEVDLGDDDVDADLAE--- 256
            ......:|                   |.::....:.:|.....||   |.|..|:.:..:.
Mosquito   194 NLPSAPVD-------------------TCTSPMPRRKQARPRRRSG---DCGPQDLSSKPSTPVP 236

  Fly   257 ---DSEEHESQMIDEEFAQADPLMELEAGTEMDDDDDV-----HDQLVDEE----IDDKPRKLGG 309
               |.:|.|..::||.....|.|.:||.    |||:|:     ..|.|||:    :.::..:...
Mosquito   237 QTLDDDETERDLLDERPDDEDELEDLED----DDDEDLKRILHRSQSVDEKLAALVANENLRTHS 297

  Fly   310 GKTRIRRPIS----------AKAVKRLSDCKPTRIQQFAALKREVKDDINDALDLAADAVII--- 361
            ..:....|.:          ::::.:||..|.......|.|.|:|        ||..|.|.:
Mosquito   298 SNSLTTTPTTTNPTSNDERRSRSLHKLSPRKTPSANSSAELLRDV--------DLETDPVAVSSA 354

  Fly   362 --------EGLSLQKAA-------------DRFDISKTVLWRRVRTNPAYMRNNR--ERPSLQEA 403
                    |.|.::|::             :...:|..:..:..:.....:::.|  .|.:|..:
Mosquito   355 SPPVSDGPENLCMKKSSSSNGTARMSDGSKESSSLSDGISGQLSKRGLLSLKDIRHLNRAALNRS 419

  Fly   404 YERLKNGHSLKSISSELQIPMSTLHRH 430
            ...:....||.|:|:.|...:|.:|.|
Mosquito   420 LGSISPPPSLSSLSNNLHPALSLMHHH 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15812	NP_523897.2	BTB	20..113	CDD:279045	27/92 (29%)
		BTB	35..118	CDD:197585	24/82 (29%)
		HTH_psq	348..392	CDD:283007	8/67 (12%)
		HTH_psq	458..501	CDD:283007
AgaP_AGAP010355	XP_311585.4	BTB	22..118	CDD:279045	27/97 (28%)
		BTB	33..118	CDD:197585	26/86 (30%)
		HTH_psq	684..727	CDD:283007
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1229475at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920