DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ND-30 and Ndufs3

DIOPT Version :9

Sequence 1:	NP_647775.1	Gene:	ND-30 / 38378	FlyBaseID:	FBgn0266582	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_080964.1	Gene:	Ndufs3 / 68349	MGIID:	1915599	Length:	263	Species:	Mus musculus

Alignment Length:	266	Identity:	164/266 - (61%)
Similarity:	192/266 - (72%)	Gaps:	8/266 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAALIRNLGARAAVAALSAKHVVPAAGSTALRMASTTPVEPKKADK-PTVRQPDAVARSHLSDFG 64
            |||....:..|..:.|.|   |...||..:: :......|...||| ||||....|....||.||
Mouse     1 MAAAAARVWCRGLLGAAS---VGRGAGRPSV-LWQHVRRESAAADKRPTVRPRSDVTHKQLSAFG 61

  Fly    65 RYVAECLPKYVQKVQLTAGDELEVLIAPEGVVPVLQFLKDHHQAQFTNLVDIAGVDVPCRKNRFE 129
            .||||.||||||:||::..||||:.|.|:||:|.|.||:||..|||.:|.|:..||||.|:||||
Mouse    62 EYVAEILPKYVQQVQVSCLDELEICIHPDGVIPTLTFLRDHTNAQFKSLADLTAVDVPTRQNRFE 126

  Fly   130 VVYNLLSLRYNSRIRVKTYTDELTPLDSACEVHKAANWYEREIWDMYGVFFANHPDLRRILTDYG 194
            :||||||||:|||||||||.|||||:||...||.||||||||:|||:||||.|||||||||||||
Mouse   127 IVYNLLSLRFNSRIRVKTYADELTPIDSIVSVHIAANWYEREVWDMFGVFFFNHPDLRRILTDYG 191

  Fly   195 FEGHPQRRDFPLSGYVELRYDDEKKRVVCEPLELAQEFRKFDLSAPWEQFPNFRNANPPAEVVPP 259
            |||||.|:||||:||||||||||.||||.||:|||||||||||::|||.||.:|.   |.|.:..
Mouse   192 FEGHPFRKDFPLTGYVELRYDDEVKRVVAEPVELAQEFRKFDLNSPWEAFPAYRQ---PPESLKL 253

  Fly   260 QAPAKK 265
            :|..||
Mouse   254 EAGDKK 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ND-30	NP_647775.1	PRK06074	60..242	CDD:235691	136/181 (75%)
Ndufs3	NP_080964.1	PRK06074	57..239	CDD:235691	136/181 (75%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850507
Domainoid	1	1.000	201	1.000	Domainoid score	I3015
eggNOG	1	0.900	-	-		E1_COG0852
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3346
Inparanoid	1	1.050	315	1.000	Inparanoid score	I2542
Isobase	1	0.950	-	0.906565	Normalized mean entropy	S2902
OMA	1	1.010	-	-		QHG51846
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005716
OrthoInspector	1	1.000	-	-		oto94614
orthoMCL	1	0.900	-	-		OOG6_101398
Panther	1	1.100	-	-	LDO	PTHR10884
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3435
SonicParanoid	1	1.000	-	-		X4118
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740