DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment BtbVII and mod(mdg4)

DIOPT Version :9

Sequence 1:	NP_647774.2	Gene:	BtbVII / 38376	FlyBaseID:	FBgn0263108	Length:	907	Species:	Drosophila melanogaster
Sequence 2:	NP_788698.1	Gene:	mod(mdg4) / 49228	FlyBaseID:	FBgn0002781	Length:	610	Species:	Drosophila melanogaster

Alignment Length:	515	Identity:	135/515 - (26%)
Similarity:	189/515 - (36%)	Gaps:	152/515 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 QQFCLRWNNHQPNFISVCSSLLHNGTLVDVTLAAEGRQLQAHKIVLSACSSYFQALFTTNPCQ-H 67
            :||.|.|||...|..:.....|..|.||||:|||||:.::||::|||.||.:|:.:||..|.. |
  Fly     5 EQFSLCWNNFNTNLSAGFHESLCRGDLVDVSLAAEGQIVKAHRLVLSVCSPFFRKMFTQMPSNTH 69

  Fly    68 PIVILKDVQYDDLKTMVDFMYYGEVNVSQEQLPHILKTAEMLKIKGLAEMPTDPANLTKSDSKSS 132
            .||.|.:|.:..||.::.|||.|||||.|:.||..:.|||.|:||||.:  .|||.....:|
  Fly    70 AIVFLNNVSHSALKDLIQFMYCGEVNVKQDALPAFISTAESLQIKGLTD--NDPAPQPPQES--- 129

  Fly   133 TDGTEMVGGAGVGTGAGNSAGSLGAGSGSSVGDSLWSSSEAQQFQQQQQQQAQQQAQQQHH---- 193
                                                |...|....||||..||:..:||..
  Fly   130 ------------------------------------SPPPAAPHVQQQQIPAQRVQRQQPRASAR 158

  Fly   194 ------------HHQQQQQLQQQQQQA------QQQQQQQQHHHHHHQQQQSGQAQAA---QTHH 237
                        ..|...|:..|...|      ||||.||.......||.|:|....|   .|:.
  Fly   159 YKIETVDDGLGDEKQSTTQIVIQTTAAPQATIVQQQQPQQAAQQIQSQQLQTGTTTTATLVSTNK 223

  Fly   238 HQMRR---TPSPLSAGTSPATRRKRLRKSSNNGSGDRNNAEEQHNSSLDAGSGAGNAGLSLAQM- 298
            ...:|   ||:..|||.      ||.:.|::      .|..:..:|:.:.|:      .:.||:
  Fly   224 RSAQRSSLTPASSSAGV------KRSKTSTS------ANVMDPLDSTTETGA------TTTAQLV 270

  Fly   299 -NQMTFGAGGGLAGHSLHAAKLLKESASAELEQQPQDSDL------------------------- 337
             .|:|.......|..    |||.::|.....:::.:..||
  Fly   271 PQQITVQTSVVSAAE----AKLHQQSPQQVRQEEAEYIDLPMELPTKSEPDYSEDHGDAAGDAEG 331

  Fly   338 ----DDGHGHLHMQ---IKPEVDIGGVNQTMPLDISGGTTPSEHDAPNSQSS--HSEPSPAHAPH 393
                ||.:|.:...   .....|.|  |||......||.|.:...|...|.|  :||.|
  Fly   332 TYVEDDTYGDMRYDDSYFTENEDAG--NQTAANTSGGGVTATTSKAVVKQQSQNYSESS------ 388

  Fly   394 PPHPPLGAASSSSGGSGSFERSFSIGGVGSVECDPDGTPSSPAVMGTKRNRVLTRQPRVK 453
                    ...:||..|:.|        .........|...|...|..:.:|..:.|:.|
  Fly   389 --------FVDTSGDQGNTE--------AQAATSASATKIPPRKRGRPKTKVEDQTPKPK 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BtbVII	NP_647774.2	BTB	24..117	CDD:279045	48/93 (52%)
BtbVII	NP_647774.2	BTB	32..117	CDD:197585	44/85 (52%)
mod(mdg4)	NP_788698.1	BTB	22..118	CDD:279045	48/95 (51%)
		BTB	33..118	CDD:197585	44/84 (52%)
		FLYWCH	452..512	CDD:282369
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	68	1.000	Domainoid score	I9675
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm40394
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23110
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	4.010